STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL48432.1PFAM: GCN5-related N-acetyltransferase; KEGG: saq:Sare_3887 hypothetical protein. (418 aa)    
Predicted Functional Partners:
ADL48378.1
Manually curated; PFAM: Soluble ligand binding domain; helix-hairpin-helix motif; KEGG: stp:Strop_3469 helix-hairpin-helix repeat-containing competence protein ComEA; SMART: Helix-hairpin-helix DNA-binding class 1.
 
    0.783
ADL45949.1
TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: stp:Strop_1911 hemolysin A; SMART: RNA-binding S4 domain protein.
  
   
 0.668
whiB-4
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
   
  
 0.637
ADL48431.1
KEGG: saq:Sare_3886 hypothetical protein.
       0.622
ADL44712.1
PFAM: isochorismatase hydrolase; KEGG: stp:Strop_1096 isochorismatase hydrolase.
     
 0.578
ADL47753.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: saq:Sare_3250 enoyl-(acyl carrier protein) reductase.
      
 0.549
ADL49059.1
KEGG: saq:Sare_2001 major facilitator transporter; manually curated; PFAM: major facilitator superfamily MFS_1.
  
    0.516
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
      
 0.512
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
      
 0.497
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.493
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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