STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nbaC3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (174 aa)    
Predicted Functional Partners:
ADL48443.1
PFAM: amidohydrolase 2; KEGG: saq:Sare_3896 amidohydrolase 2.
 
  
  0.995
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
  
  0.988
ADL48445.1
PFAM: Endoribonuclease L-PSP; KEGG: saq:Sare_3898 endoribonuclease L-PSP.
 
    0.943
ADL45590.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
     
  0.900
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
  0.900
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
 
     0.865
ADL48446.1
KEGG: saq:Sare_3899 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase.
 
     0.630
ADL48449.1
2-oxopent-4-enoate hydratase; KEGG: saq:Sare_3902 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase.
 
     0.605
ADL48562.1
TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; KEGG: stp:Strop_3593 undecaprenyl-phosphate galactose phosphotransferase; PFAM: sugar transferase.
  
  
 0.603
ADL48450.1
KEGG: saq:Sare_3903 aldehyde dehydrogenase; TIGRFAM: 2-hydroxymuconic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
   
 0.598
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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