STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADL48448.1Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (311 aa)    
Predicted Functional Partners:
ADL48447.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.999
ADL48446.1
KEGG: saq:Sare_3899 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase.
 
  
 0.991
ADL48449.1
2-oxopent-4-enoate hydratase; KEGG: saq:Sare_3902 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase.
 
  
 0.991
ADL44876.1
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; KEGG: stp:Strop_1243 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerization) domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 0.981
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.981
ADL48732.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.940
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.905
ADL44368.1
PFAM: Aldehyde Dehydrogenase; KEGG: saq:Sare_0771 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.905
ADL44539.1
PFAM: Aldehyde Dehydrogenase; KEGG: saq:Sare_0895 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.905
ADL45823.1
PFAM: Aldehyde Dehydrogenase; KEGG: mjl:Mjls_0298 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.905
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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