STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL49121.1PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sro:Sros_5363 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase. (294 aa)    
Predicted Functional Partners:
ADL47419.1
Beta-ketoacyl synthase; KEGG: cai:Caci_2598 KR domain protein; PFAM: Beta-ketoacyl synthase; KR domain protein; Enoyl-CoA hydratase/isomerase; phosphopantetheine-binding; Methyltransferase type 12; aromatic amino acid beta-eliminating lyase/threonine aldolase; alpha/beta hydrolase fold; SMART: Polyketide synthase, beta-ketoacyl synthase region; Polyketide synthase, phosphopantetheine-binding; Polyketide synthase/Fatty acid synthase, KR.
  
  
 0.676
gpsA
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: saq:Sare_1157 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.599
ADL49122.1
PFAM: helix-turn-helix HxlR type; KEGG: sro:Sros_5362 putative transcriptional regulator.
       0.576
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
      
 0.562
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
      
 0.549
ADL45176.1
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; KEGG: saq:Sare_1468 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
  
  
 0.492
ADL45687.1
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; Enoyl-CoA hydratase/isomerase; KEGG: sen:SACE_6362 putative 3-hydroxyacyl-CoA dehydrogenase.
  
  
 0.492
ADL45731.1
KEGG: hypothetical protein.
  
     0.448
ADL44029.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: msm:MSMEG_0258 oxidoreductase, short chain dehydrogenase/reductase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.425
ADL49186.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: stp:Strop_0330 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.425
Your Current Organism:
Micromonospora aurantiaca
NCBI taxonomy Id: 644283
Other names: M. aurantiaca ATCC 27029, Micromonospora aurantiaca ATCC 27029, Micromonospora aurantiaca str. ATCC 27029, Micromonospora aurantiaca strain ATCC 27029
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.