STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0004Protein of unknown function DUF721; COGs: COG5512 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives; InterPro IPR007922; KEGG: bcv:Bcav_0005 protein of unknown function DUF721; PFAM: protein of unknown function DUF721; SPTR: D0WL05 Protein in RecF-GyrB intergenic region; PFAM: Protein of unknown function (DUF721). (194 aa)    
Predicted Functional Partners:
Arch_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
     
 0.892
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
 
  
 0.884
Arch_1728
Metallophosphoesterase; COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: bcv:Bcav_0603 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: D0WK61 Ser/Thr protein phosphatase family protein; PFAM: Calcineurin-like phosphoesterase.
  
     0.770
Arch_0007
KEGG: kra:Krad_0008 hypothetical protein; SPTR: D0WL02 Putative integral membrane protein; PFAM: Transmembrane domain of unknown function (DUF3566).
 
     0.755
Arch_0799
KEGG: bcv:Bcav_1965 hypothetical protein; SPTR: D0WQH2 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3000).
  
     0.736
Arch_1515
Septum formation initiator; InterPro IPR007060; KEGG: bcv:Bcav_1019 septum formation initiator; PFAM: Septum formation initiator; SPTR: D0WQ09 Putative membrane protein; PFAM: Septum formation initiator.
  
     0.729
Arch_1231
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: jde:Jden_0711 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: D0WNM4 Helicase, UvrD/Rep family; PFAM: Domain of unknown function DUF83; UvrD/REP helicase.
  
     0.692
Arch_0204
KEGG: bcv:Bcav_3525 hypothetical protein; SPTR: C5C2S3 Putative uncharacterized protein.
  
     0.655
Arch_1514
Protein of unknown function DUF501; COGs: COG1507 conserved hypothetical protein; InterPro IPR007511; KEGG: jde:Jden_1921 protein of unknown function DUF501; PFAM: protein of unknown function DUF501; SPTR: D0WQ08 Septum formation initiator family protein; PFAM: Protein of unknown function (DUF501).
  
     0.651
Arch_0770
KEGG: bcv:Bcav_1933 DNA-binding protein; SPTR: D0WQI5 Putative DNA-binding protein; PFAM: Protein of unknown function (DUF3071).
  
     0.647
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.