STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
Arch_0019L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (555 aa)    
Predicted Functional Partners:
Arch_0021
Iron-sulfur cluster binding protein; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterProIPR003741:IPR012285:IPR004452:IPR009051:IPR 017900; KEGG: nml:Namu_1033 iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; SPTR: D0WLY3 Iron-sulfur cluster-binding protein; TIGRFAM: iron-sulfur cluster binding protein; PFAM: Domain of unknown function (DUF3390); Uncharacterised ACR, YkgG family COG1556; TIGRFAM: 2[4Fe-4S] protein, putative.
 
  
 0.908
Arch_0022
Protein of unknown function DUF162; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: nml:Namu_5228 protein of unknown function DUF162; PFAM: protein of unknown function DUF162; SPTR: A7BE65 Putative uncharacterized protein; PFAM: Uncharacterised ACR, YkgG family COG1556.
 
  
 0.863
Arch_0020
COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017; KEGG: xce:Xcel_0891 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C0W209 (S)-2-hydroxy-acid oxidase; PFAM: Cysteine-rich domain.
 
  
 0.819
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
  
 0.497
Arch_0329
Regulatory protein GntR HTH; COGs: COG2186 Transcriptional regulators; InterPro IPR011991:IPR000524:IPR011711; KEGG: bcv:Bcav_3776 regulatory protein GntR HTH; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: D0WKM6 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
  
 0.490
Arch_0265
Glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; COGs: COG0247 Fe-S oxidoreductase; InterProIPR001450:IPR004017:IPR012285:IPR017896:IPR 017753:IPR009051:IPR017900; KEGG: pac:PPA2248 sn-glycerol-3-phosphate dehydrogenase subunit C; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C2BV29 sn-glycerol-3-phosphate dehydrogenase subunit C; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; PFAM: Cysteine-rich domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit.
  
  
 0.466
Arch_0018
YhgE/Pip C-terminal domain protein; COGs: COG1511 membrane protein; InterPro IPR017500:IPR017501; KEGG: jde:Jden_0687 YhgE/Pip C-terminal domain protein; SPTR: C0W4B7 Phage infection protein; TIGRFAM: YhgE/Pip C-terminal domain protein; YhgE/Pip N-terminal domain protein; TIGRFAM: X-X-X-Leu-X-X-Gly heptad repeats; YhgE/Pip C-terminal domain; YhgE/Pip N-terminal domain.
       0.440
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
      
 0.438
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.403
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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