STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0020COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017; KEGG: xce:Xcel_0891 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C0W209 (S)-2-hydroxy-acid oxidase; PFAM: Cysteine-rich domain. (262 aa)    
Predicted Functional Partners:
Arch_0021
Iron-sulfur cluster binding protein; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterProIPR003741:IPR012285:IPR004452:IPR009051:IPR 017900; KEGG: nml:Namu_1033 iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; SPTR: D0WLY3 Iron-sulfur cluster-binding protein; TIGRFAM: iron-sulfur cluster binding protein; PFAM: Domain of unknown function (DUF3390); Uncharacterised ACR, YkgG family COG1556; TIGRFAM: 2[4Fe-4S] protein, putative.
 
 0.998
Arch_0022
Protein of unknown function DUF162; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: nml:Namu_5228 protein of unknown function DUF162; PFAM: protein of unknown function DUF162; SPTR: A7BE65 Putative uncharacterized protein; PFAM: Uncharacterised ACR, YkgG family COG1556.
 
 0.985
Arch_0019
L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.819
Arch_1670
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763:IPR016156:IPR013027:IPR004099; KEGG: cdi:DIP1748 putative oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: C2CQM4 CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain.
  
  
 0.435
Arch_0266
Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; COGs: COG3075 Anaerobic glycerol-3-phosphate dehydrogenase; InterPro IPR003953:IPR009158; KEGG: pac:PPA2249 anaerobic glycerol-3-phosphate dehydrogenase subunit B; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: D0YR90 Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; PFAM: FAD binding domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit.
  
  
 0.420
Arch_0267
Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076:IPR007419:IPR017752:IPR000447; KEGG: pac:PPA2250 anaerobic glycerol-3-phosphate dehydrogenase subunit A; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: D0YR89 Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit.
  
  
 0.409
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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