STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0028COGs: COG1292 Choline-glycine betaine transporter; InterPro IPR000060:IPR018093; KEGG: cgt:cgR_1005 hypothetical protein; PFAM: BCCT transporter; SPTR: C8NW06 BCCT family osmoprotectant transporter; TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT family transporter; TIGRFAM: choline/carnitine/betaine transport; Belongs to the BCCT transporter (TC 2.A.15) family. (614 aa)    
Predicted Functional Partners:
Arch_0049
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016162:IPR010061:IPR016161; KEGG: pac:PPA0461 methylmalonic acid semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: C0W6L2 Methylmalonate-semialdehyde dehydrogenase (Acylating); TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
  
  
 0.541
Arch_1010
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.510
Arch_0083
Transcriptional regulator, MarR family; COGs: COG4750 CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes; InterPro IPR000835:IPR002573:IPR011009; KEGG: apv:Apar_1003 transcriptional regulator, MarR family; PFAM: Choline/ethanolamine kinase; regulatory protein MarR; SPTR: A7BEG2 Putative uncharacterized protein; PFAM: Choline/ethanolamine kinase; Nucleotidyl transferase.
       0.493
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
   
  
 0.451
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.430
Arch_0029
RarD protein, DMT superfamily transporter; COGs: COG2962 permease; InterPro IPR000620:IPR004626; KEGG: pfl:PFL_3385 RarD protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: C0W1I2 DMT superfamily drug/metabolite transporter; TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: EamA-like transporter family; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); rarD protein.
       0.404
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.