STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0035Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761:IPR010982; KEGG: pac:PPA1457 LacI family transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Q6A7R0 Putative LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family. (342 aa)    
Predicted Functional Partners:
Arch_1478
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR010982; KEGG: sco:SCO5692 transcriptional regulator; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: C0W8S7 Regulatory protein LacI family protein; PFAM: Bacterial regulatory proteins, lacI family; family.
  
     0.773
Arch_1488
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR010982; KEGG: sth:STH770 LacI family transcriptional repressor; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: C0W1U4 Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family.
  
     0.724
Arch_0036
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: bcv:Bcav_1099 fructokinase; PFAM: PfkB domain protein; SPTR: C1RNV6 Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase.
 
  
 0.719
Arch_0033
Conserved hypothetical protein; InterPro IPR013781:IPR017853; KEGG: bfa:Bfae_10930 hypothetical protein; SPTR: C7MBG8 Putative uncharacterized protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
     0.664
Arch_0034
Glycoside hydrolase family 38; COGs: COG0383 Alpha-mannosidase; InterPro IPR000602:IPR015341:IPR011682:IPR011330; KEGG: pac:PPA1459 alpha-mannosidase; PFAM: glycoside hydrolase family 38; Glycoside hydrolase family 38 central region; glycosyl hydrolase 38 domain protein; SPTR: Q6A7Q8 Alpha-mannosidase; PFAM: Glycosyl hydrolases family 38 C-terminal domain; Glycosyl hydrolases family 38 N-terminal domain; Alpha mannosidase, middle domain.
 
    0.610
Arch_1122
Dihydroxyacetone kinase, phosphotransfer subunit; COGs: COG3412 conserved hypothetical protein; InterProIPR000032:IPR004701:IPR012844:IPR005698:IPR 001020; KEGG: ecm:EcSMS35_4856 phosphoenolpyruvate-protein phosphotransferase PtnE; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; SPTR: D0YPG5 PTS-dependent dihydroxyacetone kinase, DhaM subunit; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; PFAM: PTS system fructose IIA component; PTS HPr component phosphorylation site; TIGRFAM: dihydroxyacetone kinase, phosphotr [...]
   
 
 0.462
Arch_1461
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR000032:IPR005698:IPR001020; KEGG: cef:CE1830 putative PTS phosphohistidine-containing protein; PFAM: phosphoryl transfer system HPr; SPTR: A7BEU7 Putative uncharacterized protein; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
   
 
 0.459
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
   0.429
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
  
  
 0.414
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR020825:IPR005121:IPR016027:IPR009061:IPR 004532:IPR002547:IPR012340:IPR005147:IPR005146; KEGG: jde:Jden_1109 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: D0WN31 Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synt [...]
    
   0.412
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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