STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Arch_0038Alcohol dehydrogenase zinc-binding domain protein; COGs: COG1062 Zn-dependent alcohol dehydrogenase class III; InterPro IPR013154:IPR013149:IPR011032:IPR016040; KEGG: hypothetical protein; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: D0YPM1 Alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (377 aa)    
Predicted Functional Partners:
Arch_1121
COGs: COG0627 esterase; InterPro IPR000801; KEGG: cgt:cgR_1064 hypothetical protein; PFAM: putative esterase; SPTR: C2KS46 Esterase; PFAM: Putative esterase.
  
 
 0.916
Arch_1671
Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: cdi:DIP1749 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Q6NFY6 Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937.
  
  
 0.756
Arch_0043
Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR001585:IPR013785; KEGG: pac:PPA0454 transaldolase; PFAM: Transaldolase; SPTR: Q6AAL0 Transaldolase; PFAM: Transaldolase.
  
  
 0.621
Arch_0049
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016162:IPR010061:IPR016161; KEGG: pac:PPA0461 methylmalonic acid semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: C0W6L2 Methylmalonate-semialdehyde dehydrogenase (Acylating); TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
 
 0.584
tadA
CMP/dCMP deaminase zinc-binding protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
    0.525
Arch_0039
Sugar transporter; InterPro IPR005828:IPR003663:IPR016196:IPR005829; KEGG: pac:PPA0467 putative sugar transporter YfiG; PFAM: General substrate transporter; SPTR: C0W6M7 MFS family major facilitator transporter; TIGRFAM: sugar transporter; PFAM: Sugar (and other) transporter; TIGRFAM: MFS transporter, sugar porter (SP) family.
 
     0.482
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
  
 0.460
Arch_0736
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR000815:IPR016156:IPR012999:IPR 004099:IPR006258; KEGG: jde:Jden_1475 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: D0WQM8 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
 
  
 0.417
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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