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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0042Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104:IPR016040; KEGG: pac:PPA0469 putative myo-inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: C0W6K5 Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (328 aa)    
Predicted Functional Partners:
Arch_0041
Myo-inosose-2 dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307:IPR013022; KEGG: pac:PPA0468 putative myo-inositol catabolism protein; PFAM: Xylose isomerase domain protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: D0YPM5 Sugar phosphate isomerase/epimerase IolE; PFAM: Xylose isomerase-like TIM barrel.
 
 
 0.998
Arch_0048
Thiamine pyrophosphate protein central region; COGs: COG3962 Acetolactate synthase; InterPro IPR012001:IPR012000:IPR011766; KEGG: pac:PPA0459 thiamine pyrophosphate-requiring enzyme, putative acetolactate synthase; PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: D0YPL2 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate e [...]
 
  
 0.959
Arch_0047
Myo-inositol catabolism IolB domain protein; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; InterPro IPR010669:IPR011051; KEGG: rop:ROP_10680 5-deoxy-glucuronate isomerase; PFAM: Myo-inositol catabolism IolB domain protein; SPTR: D0YPL3 5-deoxy-glucuronate isomerase; PFAM: KduI/IolB family.
 
  
 0.957
Arch_0546
Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760; KEGG: lin:lin1054 hypothetical protein; PFAM: inositol monophosphatase; SPTR: A7BCA5 Putative uncharacterized protein; PFAM: Inositol monophosphatase family.
    
 0.917
Arch_0045
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002139; KEGG: rer:RER_20210 5-dehydro-2-deoxygluconokinase; PFAM: PfkB domain protein; SPTR: C0W6K8 Possible 5-dehydro-2-deoxygluconokinase; PFAM: pfkB family carbohydrate kinase.
 
  
 0.823
Arch_0043
Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR001585:IPR013785; KEGG: pac:PPA0454 transaldolase; PFAM: Transaldolase; SPTR: Q6AAL0 Transaldolase; PFAM: Transaldolase.
 
  
 0.811
Arch_0049
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016162:IPR010061:IPR016161; KEGG: pac:PPA0461 methylmalonic acid semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: C0W6L2 Methylmalonate-semialdehyde dehydrogenase (Acylating); TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
 
  
 0.696
Arch_1164
Galactokinase; COGs: COG0153 Galactokinase; InterProIPR020568:IPR000705:IPR019741:IPR006203:IPR 014721:IPR019539:IPR006204:IPR013750:IPR006206; KEGG: nca:Noca_2607 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: A1SJX6 Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Belongs to the GHMP kinase family. GalK subfamily.
  
 
 0.584
Arch_0067
dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR016040:IPR005888; KEGG: xce:Xcel_2563 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: D0WPK4 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.530
lysS-2
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR016027:IPR002313:IPR006195:IPR012340:IPR 007424:IPR007425:IPR007426:IPR004365:IPR004364:IPR018149; KEGG: cdi:DIP2138 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Q6NEX1 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: Uncharacterized conserved protein (DUF2156); tRNA synthetases class II (D, K and N); OB-fo [...]
  
    0.501
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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