STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0049COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016162:IPR010061:IPR016161; KEGG: pac:PPA0461 methylmalonic acid semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: C0W6L2 Methylmalonate-semialdehyde dehydrogenase (Acylating); TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. (497 aa)    
Predicted Functional Partners:
Arch_0949
KEGG: jde:Jden_1121 hypothetical protein; SPTR: C7R3S0 Putative uncharacterized protein.
   
 0.961
Arch_1315
Phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: bfa:Bfae_08770 phosphotransacetylase; PFAM: phosphate acetyl/butaryl transferase; SPTR: D0WNY9 Putative phosphate acetyltransferase pta; TIGRFAM: phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase.
  
 
 0.935
Arch_0430
COGs: COG1882 Pyruvate-formate lyase; InterPro IPR001150:IPR004184:IPR005949; KEGG: car:cauri_2089 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: C0VY68 Formate C-acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1.
  
 
 0.921
Arch_0431
Formate C-acetyltransferase glycine radical; COGs: COG1882 Pyruvate-formate lyase; InterPro IPR019777:IPR001150; KEGG: car:cauri_2088 formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; SPTR: C0VY69 Putative uncharacterized protein; PFAM: Glycine radical.
  
 
 0.921
Arch_0047
Myo-inositol catabolism IolB domain protein; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; InterPro IPR010669:IPR011051; KEGG: rop:ROP_10680 5-deoxy-glucuronate isomerase; PFAM: Myo-inositol catabolism IolB domain protein; SPTR: D0YPL3 5-deoxy-glucuronate isomerase; PFAM: KduI/IolB family.
 
  
 0.874
Arch_0048
Thiamine pyrophosphate protein central region; COGs: COG3962 Acetolactate synthase; InterPro IPR012001:IPR012000:IPR011766; KEGG: pac:PPA0459 thiamine pyrophosphate-requiring enzyme, putative acetolactate synthase; PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: D0YPL2 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate e [...]
  
 0.857
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
   
  
 0.805
Arch_0045
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002139; KEGG: rer:RER_20210 5-dehydro-2-deoxygluconokinase; PFAM: PfkB domain protein; SPTR: C0W6K8 Possible 5-dehydro-2-deoxygluconokinase; PFAM: pfkB family carbohydrate kinase.
 
 
 0.732
Arch_0043
Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR001585:IPR013785; KEGG: pac:PPA0454 transaldolase; PFAM: Transaldolase; SPTR: Q6AAL0 Transaldolase; PFAM: Transaldolase.
 
 
 0.718
Arch_1010
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.714
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.