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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0051ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: pac:PPA2062 ROK family transcriptional regulator; PFAM: ROK family protein; SPTR: Q6A638 Transcriptional regulator, ROK family; PFAM: ROK family; IclR helix-turn-helix domain. (389 aa)    
Predicted Functional Partners:
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
  
 
 0.957
Arch_1589
PTS system, N-acetylglucosamine-specific IIBC subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001996:IPR013013:IPR003352:IPR018113:IPR 010974:IPR011535; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: Phosph [...]
  
 
 0.937
Arch_0050
Microcystin LR degradation protein MlrC; COGs: COG5476 conserved hypothetical protein; InterPro IPR015995:IPR010799:IPR009197; KEGG: pac:PPA2061 hypothetical protein; PFAM: Microcystin LR degradation protein MlrC-like; MlrC domain protein; SPTR: Q6A639 Conserved protein; PFAM: MlrC C-terminus; Protein of unknown function (DUF1485).
       0.720
Arch_0052
Extracellular solute-binding protein family 5; COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: pac:PPA2063 putative peptide-binding transport protein; PFAM: extracellular solute-binding protein family 5; SPTR: C0W0N7 Peptide-binding transport protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.
 
   
 0.586
Arch_0726
Polyphosphate--glucose phosphotransferase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: xce:Xcel_2049 ROK family protein; PFAM: ROK family protein; PRIAM: Polyphosphate--glucose phosphotransferase; SPTR: D1BFU6 Polyphosphate glucokinase; PFAM: ROK family.
  
   
 0.558
Arch_0056
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: pac:PPA2359 putative transcriptional repressor protein; PFAM: ROK family protein; SPTR: Q6A633 Putative transcriptional repressor protein; PFAM: ROK family.
 
    
0.548
Arch_0333
COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680; KEGG: xce:Xcel_2442 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: D0WNV7 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase.
 
  
 0.456
Arch_0899
COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015813:IPR015795:IPR011037:IPR 018209:IPR015794:IPR001697; KEGG: bcv:Bcav_2215 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: D0WMQ1 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
 
   
 0.424
Arch_0470
InterPro IPR001996; KEGG: cai:Caci_8113 phosphotransferase system PTS EIIB protein; SPTR: C7QIN6 Phosphotransferase system PTS EIIB protein.
  
 
 0.405
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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