STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0058CutC family protein; COGs: COG3142 Uncharacterized protein involved in copper resistance; InterPro IPR005627; KEGG: sma:SAV_3917 homeostasis protein; PFAM: CutC family protein; SPTR: Q82GI0 Putative homeostasis protein; PFAM: CutC family; Belongs to the CutC family. (219 aa)    
Predicted Functional Partners:
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
  
  
 0.645
Arch_0158
Glycoside hydrolase, family 20, catalytic core; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015883:IPR013781:IPR017853:IPR001540; KEGG: sco:SCO4860 secreted hydrolase; PFAM: Glycoside hydrolase, family 20, catalytic core; SPTR: C8P1S6 Lacto-N-biosidase; PFAM: Glycosyl hydrolase family 20, catalytic domain.
 
     0.598
Arch_0722
Glycoside hydrolase, family 20, catalytic core; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterProIPR001540:IPR017853:IPR008979:IPR000421:IPR 013781:IPR015883; KEGG: sgr:SGR_2685 putative beta-N-acetylglucosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; coagulation factor 5/8 type domain protein; SPTR: A8REL0 Putative uncharacterized protein; PFAM: F5/8 type C domain; Glycosyl hydrolase family 20, catalytic domain; TIGRFAM: LPXTG-motif cell wall anchor domain.
 
     0.550
Arch_0050
Microcystin LR degradation protein MlrC; COGs: COG5476 conserved hypothetical protein; InterPro IPR015995:IPR010799:IPR009197; KEGG: pac:PPA2061 hypothetical protein; PFAM: Microcystin LR degradation protein MlrC-like; MlrC domain protein; SPTR: Q6A639 Conserved protein; PFAM: MlrC C-terminus; Protein of unknown function (DUF1485).
 
     0.537
Arch_0059
COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: sen:SACE_6472 putative dTDP-rhamnosyl transferase; PFAM: glycosyl transferase family 2; SPTR: C0W8B3 dTDP-rhamnosyl transferase; PFAM: Glycosyl transferase family 2.
       0.505
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.493
Arch_0057
COGs: COG3669 Alpha-L-fucosidase; InterPro IPR000933:IPR013781:IPR016286:IPR017853; KEGG: pac:PPA2070 alpha-L-fucosidase precursor; PFAM: glycoside hydrolase family 29 (alpha-L-fucosidase); PRIAM: Alpha-L-fucosidase; SMART: glycoside hydrolase family 29 (alpha-L-fucosidase); SPTR: Q6A632 Alpha-L-fucosidase; PFAM: Alpha-L-fucosidase.
 
   
 0.472
Arch_0332
COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018321:IPR006148; KEGG: xce:Xcel_1049 glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; SPTR: D0WNV6 Glucosamine-6-phosphate deaminase; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase.
 
   
 0.464
Arch_1450
InterPro IPR000387; KEGG: gym:GYMC10_3221 dual specificity protein phosphatase; SPTR: A0JXC1 Dual specificity protein phosphatase; PFAM: Protein-tyrosine phosphatase.
  
     0.453
Arch_0010
Coagulation factor 5/8 type domain protein; COGs: COG1196 Chromosome segregation ATPase; InterPro IPR000421:IPR008979; KEGG: cai:Caci_5658 ricin B lectin; PFAM: coagulation factor 5/8 type domain protein; SPTR: C7QC69 Ricin B lectin; PFAM: F5/8 type C domain.
  
     0.445
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.