STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0086dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (282 aa)    
Predicted Functional Partners:
Arch_0089
COGs: COG1898 dTDP-4-dehydrorhamnose 3 5-epimerase; InterPro IPR000888:IPR014710:IPR011051; KEGG: xce:Xcel_2560 dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; PRIAM: dTDP-4-dehydrorhamnose 3,5-epimerase; SPTR: D0WPJ1 dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase.
 
 0.999
Arch_0067
dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR016040:IPR005888; KEGG: xce:Xcel_2563 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: D0WPK4 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 
0.987
Arch_0093
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
  
 0.986
Arch_0059
COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: sen:SACE_6472 putative dTDP-rhamnosyl transferase; PFAM: glycosyl transferase family 2; SPTR: C0W8B3 dTDP-rhamnosyl transferase; PFAM: Glycosyl transferase family 2.
 
  
 0.801
Arch_0071
COGs: COG1216 glycosyltransferase; InterPro IPR001173:IPR001296; KEGG: nml:Namu_4203 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; glycosyl transferase group 1; SPTR: C1RIN5 Predicted glycosyltransferase (Fragment); PFAM: Glycosyl transferases group 1; Glycosyl transferase family 2; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type.
 
  
 0.620
Arch_0092
Rhamnosyltransferase; COGs: COG1216 glycosyltransferase; InterPro IPR001173:IPR006446; KEGG: ajs:Ajs_0541 rhamnosyltransferase; PFAM: glycosyl transferase family 2; SPTR: D0WPJ2 Rhamnosyltransferase; TIGRFAM: rhamnosyltransferase; PFAM: Glycosyl transferase family 2; TIGRFAM: L-rhamnosyltransferase.
 
  
 0.561
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
  
 0.539
Arch_0359
Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018480:IPR018481; KEGG: jde:Jden_1782 glycosyl transferase family 4; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: D0WRT0 Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; PFAM: Glycosyl transferase family 4.
     
 0.516
dcd
Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
   
    0.501
Arch_1240
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.493
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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