STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (194 aa)    
Predicted Functional Partners:
Arch_0574
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
 
 0.843
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.814
Arch_1455
Alpha/beta hydrolase fold protein; InterPro IPR000073:IPR002410; KEGG: cef:CE0596 putative prolyl aminopeptidase; PFAM: alpha/beta hydrolase fold; SPTR: Q8FS10 Putative prolyl aminopeptidase; PFAM: alpha/beta hydrolase fold.
 
      0.766
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.707
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
      0.704
Arch_0109
Appr-1-p processing domain protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: sse:Ssed_1314 hypothetical protein; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; SPTR: D0WKT6 Appr-1-p processing enzyme family domain protein; PFAM: Macro domain.
 
     0.676
Arch_0111
Oligopeptidase B; COGs: COG1770 Protease II; InterPro IPR004106:IPR001375:IPR002470; KEGG: bfa:Bfae_03460 oligopeptidase B; PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; PRIAM: Oligopeptidase B; SPTR: D0WKS9 Protease II; PFAM: Prolyl oligopeptidase, N-terminal beta-propeller domain; Prolyl oligopeptidase family.
       0.641
Arch_0451
Single-strand binding protein; InterPro IPR012340:IPR000424:IPR011344:IPR016027; KEGG: ach:Achl_2173 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: D0WRE4 Single-stranded DNA-binding protein 1; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
   
 0.627
Arch_1801
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR016027:IPR000424:IPR011344:IPR012340; KEGG: xce:Xcel_3354 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: D0WL44 Single-strand binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
   
 0.627
Arch_0393
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121:IPR014016:IPR014017:IPR000212; KEGG: bcv:Bcav_2897 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: D0WRX3 ATP-dependent DNA helicase II; PFAM: HRDC domain; UvrD/REP helicase.
  
 
 0.573
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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