STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0111Oligopeptidase B; COGs: COG1770 Protease II; InterPro IPR004106:IPR001375:IPR002470; KEGG: bfa:Bfae_03460 oligopeptidase B; PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; PRIAM: Oligopeptidase B; SPTR: D0WKS9 Protease II; PFAM: Prolyl oligopeptidase, N-terminal beta-propeller domain; Prolyl oligopeptidase family. (725 aa)    
Predicted Functional Partners:
clpP
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.718
Arch_1549
Peptidase S14 ClpP; COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907; KEGG: det:DET1086 ATP-dependent Clp protease, proteolytic subunit ClpP, putative; PFAM: peptidase S14 ClpP; SPTR: C8RU57 ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: Clp protease; Belongs to the peptidase S14 family.
   
  
 0.718
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.641
clpP-2
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.534
Arch_0395
COGs: COG5282 conserved hypothetical protein; InterPro IPR018766; KEGG: bcv:Bcav_2890 hypothetical protein; PFAM: Protein of unknown function DUF2342; SPTR: D0WRX5 Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: Uncharacterised conserved protein (DUF2342); TIGRFAM: conserved hypothetical protein.
   
  
 0.522
Arch_0112
Hypothetical protein; InterPro IPR011335; KEGG: bfa:Bfae_23020 hypothetical protein; SPTR: C2KMY9 Putative uncharacterized protein.
       0.498
Arch_0109
Appr-1-p processing domain protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: sse:Ssed_1314 hypothetical protein; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; SPTR: D0WKT6 Appr-1-p processing enzyme family domain protein; PFAM: Macro domain.
       0.470
Arch_0108
Protein of unknown function UPF0126; COGs: COG2860 membrane protein; InterPro IPR005115; KEGG: krh:KRH_07930 hypothetical protein; PFAM: protein of unknown function UPF0126; SPTR: B2GKC0 Hypothetical membrane protein; PFAM: UPF0126 domain.
       0.441
Arch_0167
Prolyl oligopeptidase; COGs: COG1505 Serine protease of the peptidase family S9A; InterPro IPR001375:IPR004106:IPR002470; KEGG: sml:Smlt4084 putative exported oligopeptidase; PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; PRIAM: Prolyl oligopeptidase; SPTR: B2FHW1 Putative exported oligoPEPTIDASE; PFAM: Prolyl oligopeptidase, N-terminal beta-propeller domain; Prolyl oligopeptidase family.
 
  
0.410
Arch_0129
Protein of unknown function DUF2183; COGs: COG4850 conserved hypothetical protein; InterPro IPR019236; KEGG: cgl:NCgl2176 hypothetical protein; PFAM: Protein of unknown function DUF2183; SPTR: D0WKK5 ABC transporter, ATP-binding protein; PFAM: Uncharacterized conserved protein (DUF2183).
 
     0.404
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.