STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0127COGs: COG1643 HrpA-like helicase; InterProIPR014001:IPR003593:IPR001650:IPR007502:IPR 011709:IPR014021:IPR010222; KEGG: jde:Jden_0240 ATP-dependent helicase HrpA; PFAM: helicase-associated domain protein; helicase domain protein; protein of unknown function DUF1605; SMART: DEAD-like helicase; AAA ATPase; helicase domain protein; SPTR: D0WKL4 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); Domain of unknown function (DUF3418); Domain of unknown function (DUF1605); TIGRFAM: ATP-dependent heli [...] (1362 aa)    
Predicted Functional Partners:
Arch_0096
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.817
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
   
  0.809
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.798
Arch_0798
3'-5' exonuclease; COGs: COG0349 Ribonuclease D; InterPro IPR012337:IPR002562:IPR002121; KEGG: bcv:Bcav_1962 3'-5' exonuclease; PFAM: 3'-5' exonuclease; HRDC domain protein; SMART: 3'-5' exonuclease; HRDC domain protein; SPTR: D0WQH3 Putative ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain; TIGRFAM: ribonuclease D.
  
  0.793
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
  0.766
Arch_0894
RNA binding S1 domain protein; COGs: COG0539 Ribosomal protein S1; InterPro IPR000110:IPR016027:IPR003029:IPR012340; KEGG: jde:Jden_1229 RNA binding S1 domain protein; PFAM: RNA binding S1 domain protein; SPTR: D0WMQ6 Ribosomal protein S1; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
  
 0.763
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
    
  0.685
Arch_0835
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR000629:IPR014001:IPR001650:IPR014021:IPR 014014:IPR011545:IPR005580; KEGG: jde:Jden_1307 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DbpA RNA-binding domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D0WN23 ATP-dependent RNA helicase DeaD; PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
 
 0.672
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
   
 
 0.671
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.653
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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