STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0130Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663:IPR011991; KEGG: mva:Mvan_4015 UbiC transcription regulator-associated domain-containing protein; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: A7BEH3 Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. (251 aa)    
Predicted Functional Partners:
Arch_0131
Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 016055:IPR005852:IPR016066; KEGG: xce:Xcel_0168 phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: D0WKG6 Phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: phosphoglucomutase, alpha [...]
       0.781
Arch_0132
Conserved hypothetical protein; COGs: COG0392 integral membrane protein; InterPro IPR005242:IPR018170; KEGG: bcv:Bcav_4032 integral membrane protein; PFAM: conserved hypothetical protein; SPTR: D0WKF9 Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein.
       0.707
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
  
  
 0.705
Arch_0133
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR008250:IPR005834:IPR006403:IPR 006416:IPR001757:IPR018303:IPR017969:IPR000150; KEGG: jde:Jden_2501 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: D0WKF6 Copper-exporting ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy [...]
       0.521
Arch_0134
InterPro IPR006121:IPR017969; KEGG: mlu:Mlut_21360 copper chaperone; PFAM: Heavy metal transport/detoxification protein; SPTR: C0W4J0 MerTP family Hg2+ permease, binding protein; PFAM: Heavy-metal-associated domain.
       0.521
Arch_0046
KEGG: sro:Sros_5538 hypothetical protein; SPTR: D0YPL4 Deoxyribose-phosphate aldolase superfamily protein.
 
     0.482
Arch_0129
Protein of unknown function DUF2183; COGs: COG4850 conserved hypothetical protein; InterPro IPR019236; KEGG: cgl:NCgl2176 hypothetical protein; PFAM: Protein of unknown function DUF2183; SPTR: D0WKK5 ABC transporter, ATP-binding protein; PFAM: Uncharacterized conserved protein (DUF2183).
       0.444
Arch_0329
Regulatory protein GntR HTH; COGs: COG2186 Transcriptional regulators; InterPro IPR011991:IPR000524:IPR011711; KEGG: bcv:Bcav_3776 regulatory protein GntR HTH; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: D0WKM6 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
  
    0.433
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.425
Arch_1060
Cupin 2 conserved barrel domain protein; InterPro IPR011051:IPR013096; KEGG: cdi:DIP0761 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Q6NIK8 Putative uncharacterized protein; PFAM: Cupin domain.
  
    0.415
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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