STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0133Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR008250:IPR005834:IPR006403:IPR 006416:IPR001757:IPR018303:IPR017969:IPR000150; KEGG: jde:Jden_2501 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: D0WKF6 Copper-exporting ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy [...] (728 aa)    
Predicted Functional Partners:
Arch_0134
InterPro IPR006121:IPR017969; KEGG: mlu:Mlut_21360 copper chaperone; PFAM: Heavy metal transport/detoxification protein; SPTR: C0W4J0 MerTP family Hg2+ permease, binding protein; PFAM: Heavy-metal-associated domain.
  
 
 0.990
Arch_1738
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR018303:IPR001757:IPR000695:IPR008250:IPR 005834; KEGG: mab:MAB_0962 cation-transporting ATPase E; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: D0WK77 Cation-transporting ATPase, E1-E2 family; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC.
 
 
0.608
Arch_0132
Conserved hypothetical protein; COGs: COG0392 integral membrane protein; InterPro IPR005242:IPR018170; KEGG: bcv:Bcav_4032 integral membrane protein; PFAM: conserved hypothetical protein; SPTR: D0WKF9 Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein.
  
    0.592
Arch_0135
KEGG: stp:Strop_4046 hypothetical protein; SPTR: D0WKF3 Putative uncharacterized protein.
       0.561
Arch_0131
Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 016055:IPR005852:IPR016066; KEGG: xce:Xcel_0168 phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: D0WKG6 Phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: phosphoglucomutase, alpha [...]
     
 0.528
Arch_0130
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663:IPR011991; KEGG: mva:Mvan_4015 UbiC transcription regulator-associated domain-containing protein; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: A7BEH3 Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
       0.519
Arch_1067
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR012336:IPR005746:IPR017936:IPR017937:IPR 012335:IPR013766:IPR006662; KEGG: cur:cur_1977 thioredoxin; PFAM: Thioredoxin domain; SPTR: B1VIY8 Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
 
  
 0.495
pgk
COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015911:IPR015824:IPR015901; KEGG: jde:Jden_1257 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: D0WMT2 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
      0.473
Arch_0139
KEGG: bcv:Bcav_2625 hypothetical protein; SPTR: D0WKD8 Putative uncharacterized protein.
     
 0.465
Arch_0136
SNARE associated Golgi protein-like protein; COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: sro:Sros_4049 alkaline phosphatase; PFAM: SNARE associated Golgi protein; SPTR: C4ELT3 Uncharacterized membrane-associated protein; PFAM: SNARE associated Golgi protein.
       0.453
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.