STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
Arch_0146Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367:IPR007167:IPR011991:IPR008988; KEGG: bfa:Bfae_31300 Mn-dependent transcriptional regulator; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; SPTR: C7MB03 Mn-dependent transcriptional regulator; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain. (225 aa)    
Predicted Functional Partners:
Arch_0145
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: car:cauri_0331 manganese ABC transport system membrane protein; PFAM: ABC-3 protein; SPTR: C3PKJ4 Manganese ABC transport system membrane protein; PFAM: ABC 3 transport family.
  
 0.737
Arch_0756
KEGG: bcv:Bcav_1909 hypothetical protein; SPTR: D0WQK7 Putative transcriptional regulatory protein.
   
    0.605
Arch_0938
COGs: COG2345 transcriptional regulator protein; InterPro IPR001845; KEGG: jde:Jden_1139 putative transcriptional regulator; PFAM: regulatory protein ArsR; SPTR: D0WMJ3 Putative DNA-binding transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family.
   
  
 0.570
dcd
Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
  
    0.545
Arch_1006
ABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
   
   0.532
Arch_0936
FeS assembly protein SufD; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR011542:IPR000825; KEGG: bcv:Bcav_2339 FeS assembly protein SufD; PFAM: SufBD protein; SPTR: A7BC52 Putative uncharacterized protein; TIGRFAM: FeS assembly protein SufD; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD, group 1.
     
 0.522
Arch_1427
COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: bcv:Bcav_1165 cell envelope-related protein transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: D0WPL0 Transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain.
   
    0.471
Arch_0934
FeS assembly ATPase SufC; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR003593:IPR003439:IPR010230; KEGG: jde:Jden_1143 FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: C0VZ94 ABC superfamily ATP binding cassette transporter, ABC protein; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC.
     
 0.464
Arch_0924
Band 7 protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001972:IPR018080:IPR001107; KEGG: bcv:Bcav_2313 band 7 protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: D0WML4 Band 7 protein; PFAM: SPFH domain / Band 7 family.
   
    0.459
Arch_0151
Multisubunit sodium/proton antiporter, MrpE subunit; COGs: COG1863 Multisubunit Na+/H+ antiporter MnhE subunit; InterPro IPR002758; KEGG: jde:Jden_2436 multisubunit Na+/H+ antiporter MnhE subunit-like protein; PFAM: cation antiporter; SPTR: D1BFC8 Multisubunit Na+/H+ antiporter, MnhE subunit; PFAM: Na+/H+ ion antiporter subunit; 2.A.63.1.
       0.441
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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