STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (193 aa)    
Predicted Functional Partners:
Arch_0555
COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: krh:KRH_11260 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: C0W772 Nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family.
  
 
 0.923
Arch_1707
COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833; KEGG: cdi:DIP0465 anaerobic ribonucleoside triphosphate reductase; SPTR: C0W489 Anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase.
    
 0.903
Arch_0148
Multisubunit sodium/proton antiporter, MrpB subunit; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001750:IPR007182:IPR003916; KEGG: bcv:Bcav_3818 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); Na+/H+ antiporter MnhB subunit-related protein; SPTR: C5C4D6 NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; Domain related to MnhB subunit of Na+/H+ antiporter; 2.A.63.1.
       0.756
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.726
Arch_0151
Multisubunit sodium/proton antiporter, MrpE subunit; COGs: COG1863 Multisubunit Na+/H+ antiporter MnhE subunit; InterPro IPR002758; KEGG: jde:Jden_2436 multisubunit Na+/H+ antiporter MnhE subunit-like protein; PFAM: cation antiporter; SPTR: D1BFC8 Multisubunit Na+/H+ antiporter, MnhE subunit; PFAM: Na+/H+ ion antiporter subunit; 2.A.63.1.
       0.658
Arch_0152
Multisubunit sodium/proton antiporter, MrpF subunit; InterPro IPR007208; KEGG: xce:Xcel_3183 multiple resistance and pH regulation protein F; PFAM: multiple resistance and pH regulation protein F; SPTR: D1C0I0 Multiple resistance and pH regulation protein F; PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF); 2.A.63.1.
       0.658
Arch_0149
Multisubunit sodium/proton antiporter, MrpC subunit; COGs: COG1006 Multisubunit Na+/H+ antiporter MnhC subunit; InterPro IPR001133; KEGG: bcv:Bcav_3817 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: C5C4D5 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; 2.A.63.1.
       0.654
Arch_0150
Multisubunit sodium/proton antiporter, MrpD subunit; COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750:IPR003918; KEGG: bcv:Bcav_3816 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: C5C4D4 NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; 2.A.63.1.
       0.654
Arch_0153
Multisubunit sodium/proton antiporter, MrpG subunit; COGs: COG1320 Multisubunit Na+/H+ antiporter MnhG subunit; InterPro IPR005133; KEGG: bcv:Bcav_3813 monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; SPTR: C5C4D1 Monovalent cation/proton antiporter, MnhG/PhaG subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; 2.A.63.1.
       0.654
Arch_0146
Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367:IPR007167:IPR011991:IPR008988; KEGG: bfa:Bfae_31300 Mn-dependent transcriptional regulator; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; SPTR: C7MB03 Mn-dependent transcriptional regulator; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
  
    0.549
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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