STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0150Multisubunit sodium/proton antiporter, MrpD subunit; COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750:IPR003918; KEGG: bcv:Bcav_3816 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: C5C4D4 NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; 2.A.63.1. (517 aa)    
Predicted Functional Partners:
Arch_0148
Multisubunit sodium/proton antiporter, MrpB subunit; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001750:IPR007182:IPR003916; KEGG: bcv:Bcav_3818 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); Na+/H+ antiporter MnhB subunit-related protein; SPTR: C5C4D6 NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; Domain related to MnhB subunit of Na+/H+ antiporter; 2.A.63.1.
 
0.999
Arch_0149
Multisubunit sodium/proton antiporter, MrpC subunit; COGs: COG1006 Multisubunit Na+/H+ antiporter MnhC subunit; InterPro IPR001133; KEGG: bcv:Bcav_3817 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: C5C4D5 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; 2.A.63.1.
 
 
 0.999
Arch_0151
Multisubunit sodium/proton antiporter, MrpE subunit; COGs: COG1863 Multisubunit Na+/H+ antiporter MnhE subunit; InterPro IPR002758; KEGG: jde:Jden_2436 multisubunit Na+/H+ antiporter MnhE subunit-like protein; PFAM: cation antiporter; SPTR: D1BFC8 Multisubunit Na+/H+ antiporter, MnhE subunit; PFAM: Na+/H+ ion antiporter subunit; 2.A.63.1.
 
 
 0.999
Arch_0153
Multisubunit sodium/proton antiporter, MrpG subunit; COGs: COG1320 Multisubunit Na+/H+ antiporter MnhG subunit; InterPro IPR005133; KEGG: bcv:Bcav_3813 monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; SPTR: C5C4D1 Monovalent cation/proton antiporter, MnhG/PhaG subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; 2.A.63.1.
 
 
 0.999
Arch_0152
Multisubunit sodium/proton antiporter, MrpF subunit; InterPro IPR007208; KEGG: xce:Xcel_3183 multiple resistance and pH regulation protein F; PFAM: multiple resistance and pH regulation protein F; SPTR: D1C0I0 Multiple resistance and pH regulation protein F; PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF); 2.A.63.1.
 
 
 0.998
Arch_0304
Proton-translocating NADH-quinone oxidoreductase, chain L; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterProIPR001516:IPR001750:IPR003945:IPR003916:IPR 018393; KEGG: bcv:Bcav_3218 proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: D0WMH2 NADH-quinone oxidoreductase, L subunit; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; manually curated; PFAM: NADH-Ubiquinone/plast [...]
 
 
0.957
Arch_0154
KEGG: art:Arth_3867 hypothetical protein; SPTR: D0WKC7 Putative uncharacterized protein.
       0.677
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.668
Arch_1252
InterPro IPR017896:IPR017900:IPR001450; KEGG: cur:cur_0829 hypothetical protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: C2BU46 Putative uncharacterized protein.
  
 
 0.668
dcd
Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
       0.654
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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