STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0152Multisubunit sodium/proton antiporter, MrpF subunit; InterPro IPR007208; KEGG: xce:Xcel_3183 multiple resistance and pH regulation protein F; PFAM: multiple resistance and pH regulation protein F; SPTR: D1C0I0 Multiple resistance and pH regulation protein F; PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF); 2.A.63.1. (86 aa)    
Predicted Functional Partners:
Arch_0148
Multisubunit sodium/proton antiporter, MrpB subunit; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001750:IPR007182:IPR003916; KEGG: bcv:Bcav_3818 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); Na+/H+ antiporter MnhB subunit-related protein; SPTR: C5C4D6 NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; Domain related to MnhB subunit of Na+/H+ antiporter; 2.A.63.1.
 
 
 0.999
Arch_0151
Multisubunit sodium/proton antiporter, MrpE subunit; COGs: COG1863 Multisubunit Na+/H+ antiporter MnhE subunit; InterPro IPR002758; KEGG: jde:Jden_2436 multisubunit Na+/H+ antiporter MnhE subunit-like protein; PFAM: cation antiporter; SPTR: D1BFC8 Multisubunit Na+/H+ antiporter, MnhE subunit; PFAM: Na+/H+ ion antiporter subunit; 2.A.63.1.
 
 
 0.999
Arch_0149
Multisubunit sodium/proton antiporter, MrpC subunit; COGs: COG1006 Multisubunit Na+/H+ antiporter MnhC subunit; InterPro IPR001133; KEGG: bcv:Bcav_3817 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: C5C4D5 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; 2.A.63.1.
 
 
 0.998
Arch_0150
Multisubunit sodium/proton antiporter, MrpD subunit; COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750:IPR003918; KEGG: bcv:Bcav_3816 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: C5C4D4 NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; 2.A.63.1.
 
 
 0.998
Arch_0153
Multisubunit sodium/proton antiporter, MrpG subunit; COGs: COG1320 Multisubunit Na+/H+ antiporter MnhG subunit; InterPro IPR005133; KEGG: bcv:Bcav_3813 monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; SPTR: C5C4D1 Monovalent cation/proton antiporter, MnhG/PhaG subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; 2.A.63.1.
 
 
 0.998
Arch_0304
Proton-translocating NADH-quinone oxidoreductase, chain L; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterProIPR001516:IPR001750:IPR003945:IPR003916:IPR 018393; KEGG: bcv:Bcav_3218 proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: D0WMH2 NADH-quinone oxidoreductase, L subunit; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; manually curated; PFAM: NADH-Ubiquinone/plast [...]
  
 
 0.885
Arch_0154
KEGG: art:Arth_3867 hypothetical protein; SPTR: D0WKC7 Putative uncharacterized protein.
       0.677
dcd
Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
       0.658
Arch_0623
Peptidoglycan-binding domain 1 protein; InterPro IPR002477; KEGG: jde:Jden_0373 hypothetical protein; PFAM: Peptidoglycan-binding domain 1 protein; SPTR: C7QZN6 Putative uncharacterized protein; PFAM: Putative peptidoglycan binding domain.
 
     0.502
nuoB
NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
   0.493
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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