STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Arch_0158Glycoside hydrolase, family 20, catalytic core; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015883:IPR013781:IPR017853:IPR001540; KEGG: sco:SCO4860 secreted hydrolase; PFAM: Glycoside hydrolase, family 20, catalytic core; SPTR: C8P1S6 Lacto-N-biosidase; PFAM: Glycosyl hydrolase family 20, catalytic domain. (468 aa)    
Predicted Functional Partners:
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
  
  
 0.990
Arch_1292
LPXTG-motif cell wall anchor domain protein; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterProIPR000421:IPR006104:IPR006102:IPR006103:IPR 011081:IPR011080:IPR013781:IPR019931:IPR017853:IPR008979:I PR006101; KEGG: apv:Apar_0102 glycoside hydrolase family 2 sugar binding; PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; Ig domain protein; coagulation factor 5/8 type domain protein; SPTR: A4K5H9 Beta-galactosidase BbgIII; TIGRFAM: LPXTG-motif cell wall anchor dom [...]
 
 0.963
Arch_1589
PTS system, N-acetylglucosamine-specific IIBC subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001996:IPR013013:IPR003352:IPR018113:IPR 010974:IPR011535; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: Phosph [...]
  
    0.945
Arch_1299
LPXTG-motif cell wall anchor domain protein; COGs: COG4409 Neuraminidase (sialidase); InterPro IPR002860:IPR019931:IPR011040; KEGG: bln:Blon_2348 exo-alpha-sialidase; PFAM: glycosyl hydrolase BNR repeat-containing protein; SPTR: B7GNQ0 Exo-alpha-sialidase; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: BNR/Asp-box repeat.
 
 0.938
Arch_0026
Exo-alpha-sialidase; COGs: COG4409 Neuraminidase (sialidase); InterPro IPR011040; KEGG: pac:PPA1560 sialidase precursor; PRIAM: Exo-alpha-sialidase; SPTR: Q44562 Sialidase; PFAM: BNR/Asp-box repeat.
 
 0.936
Arch_0722
Glycoside hydrolase, family 20, catalytic core; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterProIPR001540:IPR017853:IPR008979:IPR000421:IPR 013781:IPR015883; KEGG: sgr:SGR_2685 putative beta-N-acetylglucosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; coagulation factor 5/8 type domain protein; SPTR: A8REL0 Putative uncharacterized protein; PFAM: F5/8 type C domain; Glycosyl hydrolase family 20, catalytic domain; TIGRFAM: LPXTG-motif cell wall anchor domain.
  
  
 
0.917
Arch_0161
Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pac:PPA1454 solute-binding protein of transport system; PFAM: extracellular solute-binding protein family 1; SPTR: Q6A7R3 Solute-binding protein of transport system; PFAM: Bacterial extracellular solute-binding protein.
 
     0.807
Arch_0159
Binding-protein-dependent transport systems inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: bfa:Bfae_10970 carbohydrate ABC transporter membrane protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: C7MBH2 Carbohydrate ABC transporter membrane protein; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.780
Arch_0160
COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: bfa:Bfae_10960 carbohydrate ABC transporter membrane protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: C7MBH1 Carbohydrate ABC transporter membrane protein; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.780
Arch_1588
PTS system, glucose subfamily, IIA subunit; COGs: COG2190 Phosphotransferase system IIA components; InterPro IPR001127:IPR011055; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; TIGRFAM: PTS system, glucose subfamily, IIA component.
  
    0.629
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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