STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0164Methicillin resistance protein; COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447:IPR016181; KEGG: apr:Apre_0286 methicillin resistance protein; PFAM: Methicillin resistance protein; SPTR: C7RFS6 Methicillin resistance protein; PFAM: FemAB family. (333 aa)    
Predicted Functional Partners:
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
 
 0.926
Arch_1774
Domain of unknown function DUF1727; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR013221:IPR013564; KEGG: cur:cur_1907 putative UDP-N-acetylmuramyl tripeptide synthase; PFAM: domain of unknown function DUF1727; Mur ligase middle domain protein; SPTR: C2BT38 UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: Domain of unknown function (DUF1727); Mur ligase middle domain.
 
 
 0.922
Arch_1775
COGs: COG3442 glutamine amidotransferase; InterPro IPR017929:IPR011698; KEGG: gbr:Gbro_0441 CobB/CobQ domain protein glutamine amidotransferase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: C2BT37 Possible adenosylcobyric acid synthase, glutamine-hydrolyzing; PFAM: CobB/CobQ-like glutamine amidotransferase domain.
     
  0.900
Arch_0165
Protein of unknown function DUF201; COGs: COG3919 ATP-grasp protein; InterPro IPR003806:IPR011761:IPR005479; KEGG: apr:Apre_1663 putative ATP-grasp protein; PFAM: protein of unknown function DUF201; SPTR: C7RES1 Putative ATP-grasp protein; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain.
       0.822
Arch_0163
Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701:IPR016196:IPR001958; KEGG: kse:Ksed_04650 arabinose efflux permease family protein; PFAM: major facilitator superfamily MFS_1; SPTR: C5VDV5 Permease, major facilitator family; PFAM: Major Facilitator Superfamily.
       0.603
Arch_0166
Cupin 2 conserved barrel domain protein; COGs: COG0662 Mannose-6-phosphate isomerase; InterPro IPR013096:IPR014710:IPR011051; KEGG: sub:SUB0906 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: A8U7G9 Putative uncharacterized protein; PFAM: Cupin domain.
       0.481
Arch_0162
Conserved hypothetical protein; COGs: COG1085 Galactose-1-phosphate uridylyltransferase; InterPro IPR011146:IPR000169; KEGG: cef:CE1985 hypothetical protein; SPTR: D0WKB8 UTP--hexose-1-phosphate uridylyltransferase.
       0.438
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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