STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0189Hypothetical protein; KEGG: bcv:Bcav_3646 orotate phosphoribosyltransferase; SPTR: C0VYD8 Orotate phosphoribosyltransferase. (149 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.848
Arch_1025
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.832
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130:IPR002082:IPR006132:IPR006131; KEGG: cpf:CPF_1387 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: C2KYS1 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Aspartate carbamoyltransferase regulatory c [...]
  
  
 0.826
Arch_0190
tRNA/rRNA methyltransferase (SpoU); COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: kra:Krad_4172 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: D0WLP3 RNA methyltransferase, TrmH family; PFAM: SpoU rRNA Methylase family.
  
    0.807
carB
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR016185:IPR005480:IPR006275:IPR011761:IPR 005479:IPR013817:IPR013816:IPR005481:IPR011607:IPR005483; KEGG: gwc:GWCH70_1047 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: B6FK85 Putative uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, [...]
  
 
 0.781
Arch_1023
Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterProIPR017938:IPR012165:IPR017927:IPR008333:IPR 001433:IPR019480:IPR001834; KEGG: oih:OB1492 dihydroorotate dehydrogenase; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: B0MVE6 Putative uncharacterized protein; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorota [...]
  
  
 0.766
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.762
Arch_0604
DivIVA domain repeat protein; InterPro IPR019932:IPR019933; KEGG: bcv:Bcav_2501 hypothetical protein; SPTR: D0WR37 DivIVA domain repeat protein; TIGRFAM: DivIVA domain repeat protein; DivIVA domain; TIGRFAM: DivIVA domain; DivIVA domain repeat protein.
  
     0.748
Arch_1654
KEGG: bcv:Bcav_0533 hypothetical protein; SPTR: D0WJX6 Cell envelope-related transcriptional attenuator.
  
     0.748
Arch_0132
Conserved hypothetical protein; COGs: COG0392 integral membrane protein; InterPro IPR005242:IPR018170; KEGG: bcv:Bcav_4032 integral membrane protein; PFAM: conserved hypothetical protein; SPTR: D0WKF9 Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein.
  
     0.721
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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