STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0210COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685:IPR010920:IPR018062; KEGG: cmi:CMM_1076 putative small-conductance mechanosensitive channel; PFAM: MscS Mechanosensitive ion channel; SPTR: D0WM12 Mechanosensitive ion channel family protein; PFAM: Mechanosensitive ion channel. (541 aa)    
Predicted Functional Partners:
Arch_0212
Endonuclease/exonuclease/phosphatase; COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: mkm:Mkms_0980 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Q1BDF7 Endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase family.
 
    0.873
Arch_0211
methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579:IPR011057; KEGG: bcv:Bcav_3481 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: D1BE41 Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase.
       0.857
Arch_0213
Protein of unknown function DUF6 transmembrane; COGs: COG5006 permease DMT superfamily protein; InterPro IPR000620; KEGG: bcv:Bcav_3478 protein of unknown function DUF6 transmembrane; PFAM: protein of unknown function DUF6 transmembrane; SPTR: C0W5Q8 Integral membrane protein; PFAM: EamA-like transporter family.
 
    0.817
aroK
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
       0.471
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.429
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.422
Arch_1715
KEGG: bcv:Bcav_0620 hypothetical protein; SPTR: D0WK42 Type II secretion system protein.
  
     0.406
Arch_1595
Isochorismatase hydrolase; COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: jde:Jden_1959 isochorismatase hydrolase; PFAM: isochorismatase hydrolase; SPTR: D0WQ48 Pyrazinamidase/nicotinamidase; PFAM: Isochorismatase family.
 
  
 0.402
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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