STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Arch_0219COGs: COG0306 Phosphate/sulphate permease; InterPro IPR001204; KEGG: bcv:Bcav_3421 phosphate transporter; PFAM: phosphate transporter; SPTR: C0VYU7 PiT family inorganic phosphate transporter; PFAM: Phosphate transporter family. (337 aa)    
Predicted Functional Partners:
Arch_0220
COGs: COG1392 Phosphate transport regulator (distant homolog of PhoU); InterPro IPR018445; KEGG: xce:Xcel_0299 protein of unknown function DUF47; PFAM: Putitive phosphate transport regulator; SPTR: D0WM40 Putative Pit accessory protein; PFAM: Protein of unknown function DUF47; TIGRFAM: conserved hypothetical protein TIGR00153.
 
  
 0.991
Arch_0215
Phosphate ABC transporter, periplasmic phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
     
 0.653
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.650
Arch_0216
Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
     
 0.556
lysS-2
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR016027:IPR002313:IPR006195:IPR012340:IPR 007424:IPR007425:IPR007426:IPR004365:IPR004364:IPR018149; KEGG: cdi:DIP2138 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Q6NEX1 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: Uncharacterized conserved protein (DUF2156); tRNA synthetases class II (D, K and N); OB-fo [...]
  
    0.474
Arch_1274
Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterPro IPR004808:IPR005135; KEGG: jde:Jden_0698 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: D0WNQ6 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).
     
 0.465
Arch_0221
Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: jde:Jden_1694 amino acid carrier protein; PFAM: sodium:alanine symporter; SPTR: C0U4P6 Amino acid carrier protein; TIGRFAM: amino acid carrier protein; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein.
  
    0.459
Arch_0217
Phosphate ABC transporter, inner membrane subunit PstA; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR005672; KEGG: bcv:Bcav_3424 phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: C5C241 Phosphate ABC transporter, inner membrane subunit PstA; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA.
     
 0.444
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
  
 0.431
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
    0.430
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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