STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (747 aa)    
Predicted Functional Partners:
folE
COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602:IPR001474:IPR018234; KEGG: art:Arth_0152 GTP cyclohydrolase; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: C0W610 GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
  
    0.939
Arch_0254
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.921
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.905
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
 
   
 0.901
Arch_0253
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
 0.880
Arch_0337
Band 7 protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: cgb:cg3138 membrane protease subunit stomatin/prohibitin-like protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: Q8NLV0 Membrane protease subunits, stomatin/prohibitin homologs; PFAM: SPFH domain / Band 7 family.
   
 0.839
Arch_0924
Band 7 protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001972:IPR018080:IPR001107; KEGG: bcv:Bcav_2313 band 7 protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: D0WML4 Band 7 protein; PFAM: SPFH domain / Band 7 family.
   
 0.839
Arch_0249
COGs: COG5282 conserved hypothetical protein; InterPro IPR018766; KEGG: rsa:RSal33209_3221 putative cytoplasmic protein; PFAM: Protein of unknown function DUF2342; SPTR: D0WMC6 Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: Uncharacterised conserved protein (DUF2342); TIGRFAM: conserved hypothetical protein.
       0.838
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 
 0.825
Arch_0894
RNA binding S1 domain protein; COGs: COG0539 Ribosomal protein S1; InterPro IPR000110:IPR016027:IPR003029:IPR012340; KEGG: jde:Jden_1229 RNA binding S1 domain protein; PFAM: RNA binding S1 domain protein; SPTR: D0WMQ6 Ribosomal protein S1; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
  
   0.821
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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