STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0263Major intrinsic protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425; KEGG: jde:Jden_0486 major intrinsic protein; PFAM: major intrinsic protein; SPTR: C2KN37 MIP family major intrinsic protein channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family. (248 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
 
 0.980
Arch_1722
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR001808:IPR018490:IPR012318:IPR 014710:IPR011991; KEGG: sgr:SGR_3333 Crp/Fnr family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: D0WK55 Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
   
 0.914
Arch_0267
Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076:IPR007419:IPR017752:IPR000447; KEGG: pac:PPA2250 anaerobic glycerol-3-phosphate dehydrogenase subunit A; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: D0YR89 Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit.
 
  
 0.904
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
   
  
 0.815
Arch_0105
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932:IPR014045; KEGG: bcv:Bcav_0030 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: D0WKX0 Protein phosphatase 2C; PFAM: Protein phosphatase 2C.
    
   0.786
Arch_0910
COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: xce:Xcel_1477 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: D1BS15 Aldo/keto reductase; PFAM: Aldo/keto reductase family.
   
 
 0.776
Arch_1122
Dihydroxyacetone kinase, phosphotransfer subunit; COGs: COG3412 conserved hypothetical protein; InterProIPR000032:IPR004701:IPR012844:IPR005698:IPR 001020; KEGG: ecm:EcSMS35_4856 phosphoenolpyruvate-protein phosphotransferase PtnE; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; SPTR: D0YPG5 PTS-dependent dihydroxyacetone kinase, DhaM subunit; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; PFAM: PTS system fructose IIA component; PTS HPr component phosphorylation site; TIGRFAM: dihydroxyacetone kinase, phosphotr [...]
  
  
 0.740
Arch_0555
COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: krh:KRH_11260 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: C0W772 Nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family.
  
 
 0.645
Arch_0266
Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; COGs: COG3075 Anaerobic glycerol-3-phosphate dehydrogenase; InterPro IPR003953:IPR009158; KEGG: pac:PPA2249 anaerobic glycerol-3-phosphate dehydrogenase subunit B; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: D0YR90 Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; PFAM: FAD binding domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit.
  
    0.599
Arch_0096
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
   0.532
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.