STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Arch_0278H(+)-transporting two-sector ATPase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: bcv:Bcav_3269 H(+)-transporting two-sector ATPase; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: C5C1A2 H(+)-transporting two-sector ATPase; PFAM: Cation transport protein. (481 aa)    
Predicted Functional Partners:
Arch_0277
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037:IPR016040; KEGG: bcv:Bcav_3270 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: D0WME1 Trk-type K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
 
 
 0.952
Arch_1639
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR016040:IPR003148:IPR006037; KEGG: sro:Sros_6144 TrkA-N; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: D0YQI4 TrkA-N; PFAM: TrkA-N domain; TrkA-C domain.
 
 
 0.892
Arch_0859
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027:IPR001678; KEGG: jde:Jden_1312 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: D0WMY6 Ribosomal RNA small subunit methyltransferase B; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.569
Arch_0775
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036:IPR016040:IPR003148:IPR006037; KEGG: bcv:Bcav_1941 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: D0WQH9 Trk-type K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
  
 
 0.547
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
     
 0.541
Arch_0776
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR016040:IPR003148:IPR006037; KEGG: jde:Jden_1405 TrkA-N domain protein; PFAM: TrkA-N domain protein; SPTR: D0WQH8 Trk-type K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
  
 
 0.530
Arch_0279
DNA binding domain protein, excisionase family; InterPro IPR010093:IPR009061:IPR000843; KEGG: bcv:Bcav_3263 excision promoter, Xis; SPTR: D0WME4 Putative excisionase; TIGRFAM: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain, excisionase family.
       0.474
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.442
Arch_0148
Multisubunit sodium/proton antiporter, MrpB subunit; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001750:IPR007182:IPR003916; KEGG: bcv:Bcav_3818 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); Na+/H+ antiporter MnhB subunit-related protein; SPTR: C5C4D6 NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; Domain related to MnhB subunit of Na+/H+ antiporter; 2.A.63.1.
     
 0.434
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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