STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
Arch_0333COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680; KEGG: xce:Xcel_2442 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: D0WNV7 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. (386 aa)    
Predicted Functional Partners:
Arch_0332
COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018321:IPR006148; KEGG: xce:Xcel_1049 glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; SPTR: D0WNV6 Glucosamine-6-phosphate deaminase; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase.
 0.999
nanE
N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
  
 0.982
Arch_1589
PTS system, N-acetylglucosamine-specific IIBC subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001996:IPR013013:IPR003352:IPR018113:IPR 010974:IPR011535; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: Phosph [...]
 
  
 0.972
Arch_1588
PTS system, glucose subfamily, IIA subunit; COGs: COG2190 Phosphotransferase system IIA components; InterPro IPR001127:IPR011055; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; TIGRFAM: PTS system, glucose subfamily, IIA component.
 
  
 0.953
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.947
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
     
 0.944
Arch_0330
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: bln:Blon_0644 ROK family protein; PFAM: ROK family protein; SPTR: A7BBZ4 Putative uncharacterized protein; PFAM: ROK family.
 
  
 0.793
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
     
 0.778
nucS
Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
      0.735
Arch_1416
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: bcv:Bcav_1243 hypothetical protein; PFAM: phosphoribosyltransferase; SPTR: D0WPH2 Competence protein F; PFAM: Phosphoribosyl transferase domain.
  
    0.689
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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