STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0335Anti-sigma factor; InterPro IPR014295; KEGG: cdi:DIP0710 putative anti sigma factor; SPTR: D0WRQ3 Anti-sigma factor RshA; TIGRFAM: anti-sigma factor; TIGRFAM: anti-sigma factor, TIGR02949 family. (93 aa)    
Predicted Functional Partners:
Arch_0334
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterProIPR000838:IPR007627:IPR013249:IPR014293:IPR 014284:IPR013325:IPR013324; KEGG: bcv:Bcav_1265 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: D0WRQ2 RNA polymerase sigma-70 factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymer [...]
  
 
 0.953
Arch_0371
KEGG: cai:Caci_1238 hypothetical protein; SPTR: D0WRU2 Putative ATP/GTP-binding protein, doubtful CDS.
  
 
 0.698
whiB-4
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
 
 0.698
Arch_0324
KEGG: mpa:MAP0512c hypothetical protein; SPTR: Q743S9 Putative uncharacterized protein.
  
 
 0.633
Arch_0333
COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680; KEGG: xce:Xcel_2442 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: D0WNV7 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase.
       0.527
Arch_0332
COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018321:IPR006148; KEGG: xce:Xcel_1049 glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; SPTR: D0WNV6 Glucosamine-6-phosphate deaminase; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase.
       0.504
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.493
Arch_0102
COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635:IPR002290:IPR005543:IPR017442:IPR 005503:IPR000719:IPR011009:IPR017441:IPR008271; KEGG: xce:Xcel_0018 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; flagellar basal body-associated protein FliL; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; PASTA domain containing protein; SPTR: D0WKX3 Putative serine/threonine protein kinase; PFAM: Protein kinase domain; PASTA domain.
    
 
 0.452
Arch_0754
Serine/threonine protein kinase with PASTA sensor(s); COGs: COG2815 conserved hypothetical protein; InterProIPR011009:IPR008271:IPR020635:IPR002290:IPR 005543:IPR000719:IPR017442; KEGG: bcv:Bcav_1908 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; PASTA domain containing protein; SPTR: A7BDG0 Putative uncharacterized protein; PFAM: Protein kinase domain; PASTA domain.
    
 
 0.452
Arch_0330
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: bln:Blon_0644 ROK family protein; PFAM: ROK family protein; SPTR: A7BBZ4 Putative uncharacterized protein; PFAM: ROK family.
       0.417
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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