STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Arch_0349Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: mlu:Mlut_00220 metalloendopeptidase-like membrane protein; PFAM: Peptidase M23; SPTR: C0W8N4 Putative uncharacterized protein; PFAM: Peptidase family M23. (337 aa)    
Predicted Functional Partners:
Arch_0350
COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR017946:IPR004129; KEGG: bcv:Bcav_2653 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: D0WRR5 Putative glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase family.
       0.809
Arch_0347
Protein of unknown function DUF21; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550:IPR005170; KEGG: xce:Xcel_2484 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SPTR: C0W8N2 HCC family HlyC/CorC transporter; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain.
       0.572
Arch_0348
Protein of unknown function DUF21; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550; KEGG: xce:Xcel_2483 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: D1BCR2 CBS domain-containing protein; PFAM: CBS domain; Domain of unknown function DUF21.
       0.572
Arch_1727
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR012338:IPR005543:IPR001264:IPR001460; KEGG: bcv:Bcav_0604 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SPTR: D0WK60 Penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; PASTA domain.
  
     0.520
argS
COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR005148:IPR014729:IPR001412:IPR015945:IPR 008909:IPR001278:IPR009080; KEGG: kra:Krad_1250 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: D0WRR6 Arginine--tRNA ligase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase.
 
     0.515
Arch_0346
COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR001078:IPR001017:IPR005475:IPR011603; KEGG: bcv:Bcav_1274 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; SPTR: D0WRR3 Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2- [...]
  
  
 0.435
Arch_0352
COGs: COG0083 Homoserine kinase; InterPro IPR014721:IPR020568; KEGG: cai:Caci_1201 homoserine kinase; SPTR: D0WRS3 Homoserine kinase.
       0.410
Arch_1803
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR012338:IPR001264:IPR001460; KEGG: bcv:Bcav_4182 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: D0WL42 Penicillin-binding protein; manually curated; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
  
     0.408
Arch_1218
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR011055:IPR016047; KEGG: bcv:Bcav_2767 peptidase M23; PFAM: Peptidase M23; SPTR: D0WNL6 Putative M23 peptidase domain protein; PFAM: Peptidase family M23.
  
   
0.402
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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