STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0350COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR017946:IPR004129; KEGG: bcv:Bcav_2653 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: D0WRR5 Putative glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase family. (258 aa)    
Predicted Functional Partners:
Arch_0060
COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129:IPR017946:IPR000909; KEGG: pac:PPA1839 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: D0YTV4 Glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase family.
  
  
 
0.927
Arch_0349
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: mlu:Mlut_00220 metalloendopeptidase-like membrane protein; PFAM: Peptidase M23; SPTR: C0W8N4 Putative uncharacterized protein; PFAM: Peptidase family M23.
       0.809
Arch_0267
Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076:IPR007419:IPR017752:IPR000447; KEGG: pac:PPA2250 anaerobic glycerol-3-phosphate dehydrogenase subunit A; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: D0YR89 Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit.
  
 0.682
Arch_0266
Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; COGs: COG3075 Anaerobic glycerol-3-phosphate dehydrogenase; InterPro IPR003953:IPR009158; KEGG: pac:PPA2249 anaerobic glycerol-3-phosphate dehydrogenase subunit B; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: D0YR90 Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; PFAM: FAD binding domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit.
  
 
  0.640
Arch_0348
Protein of unknown function DUF21; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550; KEGG: xce:Xcel_2483 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: D1BCR2 CBS domain-containing protein; PFAM: CBS domain; Domain of unknown function DUF21.
  
    0.602
Arch_0347
Protein of unknown function DUF21; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550:IPR005170; KEGG: xce:Xcel_2484 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SPTR: C0W8N2 HCC family HlyC/CorC transporter; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain.
  
    0.600
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
  
 0.599
Arch_0263
Major intrinsic protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425; KEGG: jde:Jden_0486 major intrinsic protein; PFAM: major intrinsic protein; SPTR: C2KN37 MIP family major intrinsic protein channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.463
Arch_1660
COGs: COG2270 Permease of the major facilitator superfamily; InterPro IPR016196:IPR011701; KEGG: pac:PPA1044 major facilitator superfamily permease; PFAM: major facilitator superfamily MFS_1; SPTR: D0WJY4 Major facilitator family transporter; PFAM: Vacuole effluxer Atg22 like.
 
     0.432
argS
COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR005148:IPR014729:IPR001412:IPR015945:IPR 008909:IPR001278:IPR009080; KEGG: kra:Krad_1250 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: D0WRR6 Arginine--tRNA ligase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase.
       0.424
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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