STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0358Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR017945:IPR006070:IPR004388; KEGG: art:Arth_2617 translation factor SUA5; PFAM: SUA5/yciO/yrdC domain; SPTR: C1RKE7 Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. (215 aa)    
Predicted Functional Partners:
Arch_0357
protein-(glutamine-N5) methyltransferase, release factor-specific; COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR002052:IPR007848:IPR004556:IPR019874; KEGG: bln:Blon_0576 modification methylase, HemK family; PFAM: methyltransferase small; SPTR: D0WRS8 Protein-(Glutamine-N5) methyltransferase; TIGRFAM: protein-(glutamine-N5) methyltransferase, release factor-specific; modification methylase, HemK family; PFAM: Methyltransferase small domain; TIGRFAM: HemK family putative methylases; protein-(glutamine-N5) methyltransferase, release factor-specific.
 
  
 0.980
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.852
Arch_0359
Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018480:IPR018481; KEGG: jde:Jden_1782 glycosyl transferase family 4; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: D0WRT0 Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; PFAM: Glycosyl transferase family 4.
       0.850
Arch_0360
Hypothetical protein; KEGG: pct:PC1_2686 sulphate transporter; SPTR: Q9I537 Putative uncharacterized protein.
       0.773
Arch_1336
Protein of unknown function UPF0079; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: xce:Xcel_0674 protein of unknown function UPF0079; PFAM: protein of unknown function UPF0079; SPTR: D0WP55 ATP/GTP hydrolase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein.
 
  
 0.627
atpB
ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
     
 0.611
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 
 0.611
rpmE
Ribosomal protein L31; Binds the 23S rRNA.
     
 0.610
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
  
    0.601
Arch_1334
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: xce:Xcel_0675 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: D0WP53 Universal bacterial protein YeaZ; PFAM: Glycoprotease family.
    
 0.587
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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