STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
nucSProtein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (231 aa)    
Predicted Functional Partners:
Arch_0371
KEGG: cai:Caci_1238 hypothetical protein; SPTR: D0WRU2 Putative ATP/GTP-binding protein, doubtful CDS.
     
 0.884
Arch_0369
Protein of unknown function DUF2550; InterPro IPR019675; KEGG: kra:Krad_1272 hypothetical protein; PFAM: Protein of unknown function DUF2550; SPTR: A6W7H1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2550).
     
 0.795
Arch_0333
COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680; KEGG: xce:Xcel_2442 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: D0WNV7 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase.
      0.735
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.724
Arch_0869
InterPro IPR009061:IPR000551; KEGG: bcv:Bcav_2099 transcriptional regulator, MerR family; SMART: regulatory protein MerR; SPTR: C5C6E6 Transcriptional regulator, MerR family.
  
     0.682
Arch_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 
 0.658
Arch_0372
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639:IPR000073; KEGG: bcv:Bcav_1326 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: D0WRU3 Putative SHCHC synthase; PFAM: alpha/beta hydrolase fold.
       0.647
atpD
ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
       0.623
Arch_0368
ATPase, F1 complex, delta/epsilon subunit; COGs: COG0355 F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit); InterPro IPR020546; KEGG: bcv:Bcav_1308 H+transporting two-sector ATPase delta/epsilon subunit; PFAM: ATPase, F1 complex, delta/epsilon subunit-like; SPTR: C5C1U9 H+transporting two-sector ATPase delta/epsilon subunit; PFAM: ATP synthase, Delta/Epsilon chain, beta-sandwich domain.
       0.613
rbpA
Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
     0.583
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.