STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Arch_0388Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (788 aa)    
Predicted Functional Partners:
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.997
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.996
Arch_0131
Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 016055:IPR005852:IPR016066; KEGG: xce:Xcel_0168 phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: D0WKG6 Phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: phosphoglucomutase, alpha [...]
  
 
 0.989
Arch_0385
Trehalose synthase; COGs: COG0366 Glycosidase; InterProIPR013781:IPR006047:IPR012810:IPR006589:IPR 017853; KEGG: xce:Xcel_2418 trehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: D1BCY4 Trehalose synthase; TIGRFAM: trehalose synthase; PFAM: Alpha amylase, catalytic domain; TIGRFAM: trehalose synthase.
  
 0.987
Arch_0469
COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR013781:IPR003385:IPR017853; KEGG: bcv:Bcav_2633 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: D0WRE1 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: 4-alpha-glucanotransferase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; 4-alpha-glucanotransferase.
 
 
 0.978
Arch_0391
Glycogen debranching enzyme GlgX; COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterProIPR013783:IPR013781:IPR004193:IPR006047:IPR 011837:IPR006589:IPR017853:IPR014756; KEGG: bcv:Bcav_1345 glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: D0WRW1 Glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: glyc [...]
  
 
 0.964
Arch_0802
Glycogen debranching enzyme GlgX; COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterProIPR017853:IPR014756:IPR006589:IPR013783:IPR 013781:IPR011837:IPR004193:IPR006047; KEGG: kra:Krad_3073 glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: D0WQH0 Glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: glyc [...]
  
 
 0.964
Arch_0927
Glycogen synthase; COGs: COG0438 Glycosyltransferase; InterPro IPR019793:IPR011875:IPR001296; KEGG: bcv:Bcav_2317 glycogen synthase; PFAM: glycosyl transferase group 1; SPTR: D0WML0 Glycogen synthase; TIGRFAM: glycogen synthase; PFAM: Glycosyl transferases group 1; TIGRFAM: glycogen synthase, Corynebacterium family.
  
 0.954
glgE
Alpha amylase catalytic region; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
  
 
 0.910
Arch_0800
Malto-oligosyltrehalose trehalohydrolase; COGs: COG0296 1 4-alpha-glucan branching enzyme; InterProIPR017853:IPR014756:IPR006589:IPR012768:IPR 013783:IPR013781:IPR004193:IPR006047; KEGG: bcv:Bcav_1971 malto-oligosyltrehalose trehalohydrolase; PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; SPTR: C5C5N5 Malto-oligosyltrehalose trehalohydrolase; TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: Alpha amylase, catalytic domain; TIGRFAM: malto-oligosyltrehalose trehalohydrolase.
  
 
 0.852
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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