Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Arch_0002 | Arch_0319 | Arch_0002 | Arch_0319 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC. | 0.747 |
| Arch_0002 | Arch_0393 | Arch_0002 | Arch_0393 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121:IPR014016:IPR014017:IPR000212; KEGG: bcv:Bcav_2897 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: D0WRX3 ATP-dependent DNA helicase II; PFAM: HRDC domain; UvrD/REP helicase. | 0.998 |
| Arch_0002 | Arch_0782 | Arch_0002 | Arch_0782 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | SNF2-related protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR014021:IPR000330; KEGG: bfa:Bfae_05330 DNA/RNA helicase, superfamily II, SNF2 family; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: C7MHJ1 DNA/RNA helicase, superfamily II, SNF2 family; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | 0.975 |
| Arch_0002 | Arch_1230 | Arch_0002 | Arch_1230 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: jde:Jden_0712 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: D0WNM3 ATP-dependent DNA helicase; PFAM: UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. | 0.667 |
| Arch_0002 | Arch_1231 | Arch_0002 | Arch_1231 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: jde:Jden_0711 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: D0WNM4 Helicase, UvrD/Rep family; PFAM: Domain of unknown function DUF83; UvrD/REP helicase. | 0.768 |
| Arch_0002 | Arch_1685 | Arch_0002 | Arch_1685 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | InterPro IPR005094; KEGG: lxx:Lxx07700 mobilization protein; PFAM: Relaxase/mobilization nuclease family protein; SPTR: C2BRG6 Possible mobilization protein; PFAM: Relaxase/Mobilisation nuclease domain. | 0.879 |
| Arch_0002 | polA | Arch_0002 | Arch_0896 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
| Arch_0002 | recA | Arch_0002 | Arch_0649 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.898 |
| Arch_0002 | sbcD | Arch_0002 | Arch_0320 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.755 |
| Arch_0002 | topA | Arch_0002 | Arch_1704 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.870 |
| Arch_0319 | Arch_0002 | Arch_0319 | Arch_0002 | SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.747 |
| Arch_0319 | Arch_0393 | Arch_0319 | Arch_0393 | SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC. | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121:IPR014016:IPR014017:IPR000212; KEGG: bcv:Bcav_2897 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: D0WRX3 ATP-dependent DNA helicase II; PFAM: HRDC domain; UvrD/REP helicase. | 0.999 |
| Arch_0319 | Arch_0782 | Arch_0319 | Arch_0782 | SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC. | SNF2-related protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR014021:IPR000330; KEGG: bfa:Bfae_05330 DNA/RNA helicase, superfamily II, SNF2 family; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: C7MHJ1 DNA/RNA helicase, superfamily II, SNF2 family; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | 0.504 |
| Arch_0319 | Arch_1231 | Arch_0319 | Arch_1231 | SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC. | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: jde:Jden_0711 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: D0WNM4 Helicase, UvrD/Rep family; PFAM: Domain of unknown function DUF83; UvrD/REP helicase. | 0.482 |
| Arch_0319 | Arch_1685 | Arch_0319 | Arch_1685 | SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC. | InterPro IPR005094; KEGG: lxx:Lxx07700 mobilization protein; PFAM: Relaxase/mobilization nuclease family protein; SPTR: C2BRG6 Possible mobilization protein; PFAM: Relaxase/Mobilisation nuclease domain. | 0.518 |
| Arch_0319 | polA | Arch_0319 | Arch_0896 | SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.991 |
| Arch_0319 | recA | Arch_0319 | Arch_0649 | SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.910 |
| Arch_0319 | sbcD | Arch_0319 | Arch_0320 | SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC. | Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.999 |
| Arch_0319 | topA | Arch_0319 | Arch_1704 | SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.962 |
| Arch_0393 | Arch_0002 | Arch_0393 | Arch_0002 | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121:IPR014016:IPR014017:IPR000212; KEGG: bcv:Bcav_2897 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: D0WRX3 ATP-dependent DNA helicase II; PFAM: HRDC domain; UvrD/REP helicase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.998 |
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