STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0414ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439; KEGG: blt:Balat_1147 putative ABC transporter ATP-binding protein; PFAM: ABC transporter related; SPTR: C6AJB3 Putative ABC transporter ATP-binding protein; PFAM: ABC transporter. (242 aa)    
Predicted Functional Partners:
Arch_0413
InterPro IPR003838; KEGG: bcv:Bcav_2825 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: C5V906 ABC transporter integral membrane protein; PFAM: Predicted permease.
 
 
 0.948
Arch_0416
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712; KEGG: bcv:Bcav_2821 histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: D0WS36 Putative signal transduction histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
    0.822
Arch_0415
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR011991:IPR000792:IPR001789:IPR011006:IPR 016032; KEGG: bcv:Bcav_2822 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: D0WS35 Two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
   
   0.784
Arch_0625
Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: jde:Jden_0375 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: D0YSN3 Putative macrolide export ATP-binding/permease protein MacB; PFAM: Predicted permease.
 
 
 0.760
Arch_0445
Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: cmi:CMM_2031 putative ABC transporter, permease component; PFAM: protein of unknown function DUF214; SPTR: C0W202 ABC superfamily ATP binding cassette transporter, permease protein; PFAM: Predicted permease.
 
 
 0.752
Arch_0788
Protein of unknown function DUF214; InterPro IPR003838; KEGG: cdl:CDR20291_1803 ABC transporter, permease protein; PFAM: protein of unknown function DUF214; SPTR: Q187I6 ABC transporter, permease protein; manually curated; PFAM: Predicted permease.
  
 
 0.633
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
    0.601
Arch_0443
KEGG: xce:Xcel_2511 hypothetical protein; SPTR: C0W204 Putative uncharacterized protein.
  
 
 0.593
Arch_1486
ABC transporter ATP-binding protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; KEGG: rsa:RSal33209_0879 ABC transporter ATP-binding protein; SPTR: A9WQH2 ABC transporter ATP-binding protein; PFAM: Adenovirus IVa2 protein.
 
  
 0.590
Arch_0690
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: jde:Jden_1534 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: D1BF11 ATPase component of Mn/Zn ABC-type transporter; PFAM: ABC transporter.
 
    0.589
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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