STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0432COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR001989:IPR007197:IPR012838; KEGG: jde:Jden_1397 pyruvate formate-lyase activating enzyme; PFAM: Radical SAM domain protein; PRIAM: [Formate-C-acetyltransferase]-activating enzyme; SPTR: C0VY70 [formate-C-acetyltransferase]-activating enzyme; TIGRFAM: pyruvate formate-lyase activating enzyme; PFAM: Radical SAM superfamily; TIGRFAM: pyruvate formate-lyase 1-activating enzyme. (308 aa)    
Predicted Functional Partners:
Arch_0430
COGs: COG1882 Pyruvate-formate lyase; InterPro IPR001150:IPR004184:IPR005949; KEGG: car:cauri_2089 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: C0VY68 Formate C-acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1.
  
 0.986
Arch_0431
Formate C-acetyltransferase glycine radical; COGs: COG1882 Pyruvate-formate lyase; InterPro IPR019777:IPR001150; KEGG: car:cauri_2088 formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; SPTR: C0VY69 Putative uncharacterized protein; PFAM: Glycine radical.
 
  
 0.973
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
     
 0.417
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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