| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Arch_0373 | Arch_0433 | Arch_0373 | Arch_0433 | KEGG: xce:Xcel_2425 hypothetical protein; SPTR: D0WRU4 Putative cellulose-binding protein; PFAM: DivIVA protein. | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | 0.535 |
| Arch_0373 | Arch_0680 | Arch_0373 | Arch_0680 | KEGG: xce:Xcel_2425 hypothetical protein; SPTR: D0WRU4 Putative cellulose-binding protein; PFAM: DivIVA protein. | Protein of unknown function YGGT; InterPro IPR003425; KEGG: fra:Francci3_1422 hypothetical protein; PFAM: protein of unknown function YGGT; SPTR: C2BWZ3 Transmembrane protein; PFAM: YGGT family. | 0.411 |
| Arch_0433 | Arch_0373 | Arch_0433 | Arch_0373 | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | KEGG: xce:Xcel_2425 hypothetical protein; SPTR: D0WRU4 Putative cellulose-binding protein; PFAM: DivIVA protein. | 0.535 |
| Arch_0433 | Arch_0434 | Arch_0433 | Arch_0434 | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | DEAD/DEAH box helicase domain protein; COGs: COG4581 Superfamily II RNA helicase; InterPro IPR014021:IPR001650:IPR011545:IPR014001; KEGG: nfa:nfa37840 putative helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D0WRH3 Putative ATP-dependent helicase; PFAM: Domain of unknown function (DUF3516); Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | 0.818 |
| Arch_0433 | Arch_0435 | Arch_0433 | Arch_0435 | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761:IPR010982; KEGG: pac:PPA2330 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: D0YQM2 LacI family transcription regulator; PFAM: Bacterial regulatory proteins, lacI family; family. | 0.774 |
| Arch_0433 | Arch_0678 | Arch_0433 | Arch_0678 | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR011324:IPR003730; KEGG: tfu:Tfu_1114 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: Q47QW5 Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726. | 0.815 |
| Arch_0433 | Arch_0680 | Arch_0433 | Arch_0680 | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | Protein of unknown function YGGT; InterPro IPR003425; KEGG: fra:Francci3_1422 hypothetical protein; PFAM: protein of unknown function YGGT; SPTR: C2BWZ3 Transmembrane protein; PFAM: YGGT family. | 0.633 |
| Arch_0433 | Arch_0681 | Arch_0433 | Arch_0681 | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | DivIVA domain protein; InterPro IPR019933:IPR007793; KEGG: xce:Xcel_1291 DivIVA family protein; PFAM: DivIVA family protein; SPTR: D0WQV0 Cell division protein, DivIVA family; TIGRFAM: DivIVA domain; PFAM: DivIVA protein; TIGRFAM: DivIVA domain. | 0.544 |
| Arch_0433 | Arch_0750 | Arch_0433 | Arch_0750 | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterProIPR012337:IPR000305:IPR006055:IPR006054:IPR 013520; KEGG: bcv:Bcav_1900 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; SPTR: D0WQL3 Putative DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family. | 0.493 |
| Arch_0433 | Arch_1082 | Arch_0433 | Arch_1082 | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | KEGG: bcv:Bcav_1606 hypothetical protein; SPTR: D0WNC7 Putative uncharacterized protein. | 0.516 |
| Arch_0433 | murF | Arch_0433 | Arch_0670 | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.577 |
| Arch_0433 | sepF | Arch_0433 | Arch_0679 | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.847 |
| Arch_0434 | Arch_0433 | Arch_0434 | Arch_0433 | DEAD/DEAH box helicase domain protein; COGs: COG4581 Superfamily II RNA helicase; InterPro IPR014021:IPR001650:IPR011545:IPR014001; KEGG: nfa:nfa37840 putative helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D0WRH3 Putative ATP-dependent helicase; PFAM: Domain of unknown function (DUF3516); Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | 0.818 |
| Arch_0434 | Arch_0435 | Arch_0434 | Arch_0435 | DEAD/DEAH box helicase domain protein; COGs: COG4581 Superfamily II RNA helicase; InterPro IPR014021:IPR001650:IPR011545:IPR014001; KEGG: nfa:nfa37840 putative helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D0WRH3 Putative ATP-dependent helicase; PFAM: Domain of unknown function (DUF3516); Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761:IPR010982; KEGG: pac:PPA2330 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: D0YQM2 LacI family transcription regulator; PFAM: Bacterial regulatory proteins, lacI family; family. | 0.773 |
| Arch_0435 | Arch_0433 | Arch_0435 | Arch_0433 | Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761:IPR010982; KEGG: pac:PPA2330 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: D0YQM2 LacI family transcription regulator; PFAM: Bacterial regulatory proteins, lacI family; family. | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | 0.774 |
| Arch_0435 | Arch_0434 | Arch_0435 | Arch_0434 | Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761:IPR010982; KEGG: pac:PPA2330 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: D0YQM2 LacI family transcription regulator; PFAM: Bacterial regulatory proteins, lacI family; family. | DEAD/DEAH box helicase domain protein; COGs: COG4581 Superfamily II RNA helicase; InterPro IPR014021:IPR001650:IPR011545:IPR014001; KEGG: nfa:nfa37840 putative helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D0WRH3 Putative ATP-dependent helicase; PFAM: Domain of unknown function (DUF3516); Helicase conserved C-terminal domain; DEAD/DEAH box helicase. | 0.773 |
| Arch_0678 | Arch_0433 | Arch_0678 | Arch_0433 | Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR011324:IPR003730; KEGG: tfu:Tfu_1114 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: Q47QW5 Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726. | Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family. | 0.815 |
| Arch_0678 | Arch_0680 | Arch_0678 | Arch_0680 | Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR011324:IPR003730; KEGG: tfu:Tfu_1114 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: Q47QW5 Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726. | Protein of unknown function YGGT; InterPro IPR003425; KEGG: fra:Francci3_1422 hypothetical protein; PFAM: protein of unknown function YGGT; SPTR: C2BWZ3 Transmembrane protein; PFAM: YGGT family. | 0.708 |
| Arch_0678 | Arch_0681 | Arch_0678 | Arch_0681 | Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR011324:IPR003730; KEGG: tfu:Tfu_1114 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: Q47QW5 Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726. | DivIVA domain protein; InterPro IPR019933:IPR007793; KEGG: xce:Xcel_1291 DivIVA family protein; PFAM: DivIVA family protein; SPTR: D0WQV0 Cell division protein, DivIVA family; TIGRFAM: DivIVA domain; PFAM: DivIVA protein; TIGRFAM: DivIVA domain. | 0.511 |
| Arch_0678 | murF | Arch_0678 | Arch_0670 | Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR011324:IPR003730; KEGG: tfu:Tfu_1114 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: Q47QW5 Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.507 |