STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0437PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: xce:Xcel_0908 PfkB domain protein; PFAM: PfkB domain protein; SPTR: D0YQL2 Carbohydrate kinase; PFAM: pfkB family carbohydrate kinase. (366 aa)    
Predicted Functional Partners:
Arch_0438
COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR013785:IPR000887; KEGG: tau:Tola_0229 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: D0YQL3 Khg/kdpg aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase.
 
 0.992
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.948
Arch_0860
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR011060:IPR000056:IPR013785; KEGG: bcv:Bcav_2050 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: D0WMY5 Ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
  
 0.847
Arch_0440
COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterProIPR016040:IPR013328:IPR013131:IPR013118:IPR 008927; KEGG: pac:PPA2328 D-mannonate oxidoreductase; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: D0YQL5 D-mannonate oxidoreductase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
     
 0.657
Arch_0436
COGs: COG1904 Glucuronate isomerase; InterPro IPR003766; KEGG: art:Arth_0502 glucuronate isomerase; PFAM: Glucuronate isomerase; PRIAM: Glucuronate isomerase; SPTR: D0YQL1 Glucuronate isomerase; PFAM: Glucuronate isomerase.
 
   
 0.649
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
  
  
 0.592
Arch_0435
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761:IPR010982; KEGG: pac:PPA2330 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: D0YQM2 LacI family transcription regulator; PFAM: Bacterial regulatory proteins, lacI family; family.
 
    0.479
Arch_0441
Hypothetical protein; KEGG: ach:Achl_0779 oxidoreductase domain protein; SPTR: B8HC64 Oxidoreductase domain protein.
  
  
 0.447
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.411
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.