STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
Arch_0441Hypothetical protein; KEGG: ach:Achl_0779 oxidoreductase domain protein; SPTR: B8HC64 Oxidoreductase domain protein. (110 aa)    
Predicted Functional Partners:
Arch_0041
Myo-inosose-2 dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307:IPR013022; KEGG: pac:PPA0468 putative myo-inositol catabolism protein; PFAM: Xylose isomerase domain protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: D0YPM5 Sugar phosphate isomerase/epimerase IolE; PFAM: Xylose isomerase-like TIM barrel.
  
  
 0.759
Arch_0048
Thiamine pyrophosphate protein central region; COGs: COG3962 Acetolactate synthase; InterPro IPR012001:IPR012000:IPR011766; KEGG: pac:PPA0459 thiamine pyrophosphate-requiring enzyme, putative acetolactate synthase; PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: D0YPL2 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate e [...]
  
  
 0.752
Arch_0047
Myo-inositol catabolism IolB domain protein; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; InterPro IPR010669:IPR011051; KEGG: rop:ROP_10680 5-deoxy-glucuronate isomerase; PFAM: Myo-inositol catabolism IolB domain protein; SPTR: D0YPL3 5-deoxy-glucuronate isomerase; PFAM: KduI/IolB family.
  
  
 0.750
Arch_1164
Galactokinase; COGs: COG0153 Galactokinase; InterProIPR020568:IPR000705:IPR019741:IPR006203:IPR 014721:IPR019539:IPR006204:IPR013750:IPR006206; KEGG: nca:Noca_2607 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: A1SJX6 Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Belongs to the GHMP kinase family. GalK subfamily.
  
 
 0.584
Arch_0437
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: xce:Xcel_0908 PfkB domain protein; PFAM: PfkB domain protein; SPTR: D0YQL2 Carbohydrate kinase; PFAM: pfkB family carbohydrate kinase.
  
  
 0.575
Arch_0067
dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR016040:IPR005888; KEGG: xce:Xcel_2563 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: D0WPK4 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.530
Arch_0440
COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterProIPR016040:IPR013328:IPR013131:IPR013118:IPR 008927; KEGG: pac:PPA2328 D-mannonate oxidoreductase; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: D0YQL5 D-mannonate oxidoreductase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
     
 0.515
lysS-2
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR016027:IPR002313:IPR006195:IPR012340:IPR 007424:IPR007425:IPR007426:IPR004365:IPR004364:IPR018149; KEGG: cdi:DIP2138 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Q6NEX1 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: Uncharacterized conserved protein (DUF2156); tRNA synthetases class II (D, K and N); OB-fo [...]
  
    0.501
lysS
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR004365:IPR004364:IPR012340:IPR006195:IPR 002313:IPR016027:IPR018149; KEGG: jde:Jden_2092 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: D0WLW0 Lysine--tRNA ligase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.481
Arch_0442
Hypothetical protein; KEGG: mno:Mnod_6520 chromosome segregation ATPase-like protein; SPTR: B8IDC3 Chromosome segregation ATPase-like protein; TIGRFAM: LPXTG-motif cell wall anchor domain.
       0.465
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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