STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Arch_0451Single-strand binding protein; InterPro IPR012340:IPR000424:IPR011344:IPR016027; KEGG: ach:Achl_2173 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: D0WRE4 Single-stranded DNA-binding protein 1; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). (186 aa)    
Predicted Functional Partners:
Arch_1801
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR016027:IPR000424:IPR011344:IPR012340; KEGG: xce:Xcel_3354 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: D0WL44 Single-strand binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
  
  
 0.919
Arch_1646
COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003593:IPR008921:IPR003959:IPR012763; KEGG: rsa:RSal33209_3356 DNA polymerase III subunits gamma and tau; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: A7BAA1 Putative uncharacterized protein; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, subunits gamma and tau.
 
 
 
 0.827
Arch_0685
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR016195:IPR016027:IPR003141:IPR004805:IPR 004013:IPR011708:IPR004365; KEGG: jde:Jden_1086 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: D0WQU6 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA poly [...]
   
 
 0.800
Arch_0857
Primosome assembly protein PriA; COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; KEGG: tfu:Tfu_1073 primosome assembly protein PriA; SPTR: D0WMZ0 Primosomal protein; TIGRFAM: primosomal protein N'; glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type.
 
 
 
 0.792
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.789
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.726
rpsB
COGs: COG0052 Ribosomal protein S2; InterPro IPR018130:IPR001865:IPR005706; KEGG: xce:Xcel_1180 ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: C0W045 Ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
   
  0.678
rplJ
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
    0.661
Arch_0346
COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR001078:IPR001017:IPR005475:IPR011603; KEGG: bcv:Bcav_1274 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; SPTR: D0WRR3 Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2- [...]
    
  0.659
Arch_1231
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: jde:Jden_0711 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: D0WNM4 Helicase, UvrD/Rep family; PFAM: Domain of unknown function DUF83; UvrD/REP helicase.
 
  
 0.659
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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