STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0451Single-strand binding protein; InterPro IPR012340:IPR000424:IPR011344:IPR016027; KEGG: ach:Achl_2173 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: D0WRE4 Single-stranded DNA-binding protein 1; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). (186 aa)    
Predicted Functional Partners:
Arch_1801
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR016027:IPR000424:IPR011344:IPR012340; KEGG: xce:Xcel_3354 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: D0WL44 Single-strand binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
  
  
  0.913
Arch_1646
COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003593:IPR008921:IPR003959:IPR012763; KEGG: rsa:RSal33209_3356 DNA polymerase III subunits gamma and tau; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: A7BAA1 Putative uncharacterized protein; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, subunits gamma and tau.
 
 
 
 0.889
Arch_0685
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR016195:IPR016027:IPR003141:IPR004805:IPR 004013:IPR011708:IPR004365; KEGG: jde:Jden_1086 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: D0WQU6 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA poly [...]
   
 
 0.872
Arch_0857
Primosome assembly protein PriA; COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; KEGG: tfu:Tfu_1073 primosome assembly protein PriA; SPTR: D0WMZ0 Primosomal protein; TIGRFAM: primosomal protein N'; glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type.
 
 
 
 0.781
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.747
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.689
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
    0.686
Arch_1231
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: jde:Jden_0711 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: D0WNM4 Helicase, UvrD/Rep family; PFAM: Domain of unknown function DUF83; UvrD/REP helicase.
 
  
 0.656
rplJ
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
    0.654
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
 
 0.624
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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