STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
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[Homology]
Score
Arch_0474Endothelin-converting enzyme 1; COGs: COG3590 metalloendopeptidase; InterPro IPR018497:IPR008753; KEGG: xce:Xcel_1104 neprilysin; PFAM: peptidase M13; Peptidase M13, neprilysin-like; PRIAM: Endothelin-converting enzyme 1; SPTR: D1BJV6 Endothelin-converting enzyme; PFAM: Peptidase family M13. (666 aa)    
Predicted Functional Partners:
Arch_0475
COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR011860; KEGG: bcv:Bcav_2620 ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; SPTR: D1BJV4 Ribose 5-phosphate isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerase, RpiB/LacA/LacB family; manually curated; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerases, RpiB/LacA/LacB family.
       0.631
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.600
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
      0.588
Arch_0473
COGs: COG0308 Aminopeptidase N; InterPro IPR014782:IPR012778; KEGG: bcv:Bcav_2630 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: D0WRD5 Aminopeptidase; TIGRFAM: aminopeptidase N; PFAM: Domain of unknown function (DUF3358); Peptidase family M1; TIGRFAM: aminopeptidase N, Streptomyces lividans type.
 
   
 0.516
Arch_0872
COGs: COG0308 Aminopeptidase N; InterPro IPR014782:IPR016059:IPR012778; KEGG: kse:Ksed_24070 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: C7NFC1 Aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Peptidase family M1; Domain of unknown function (DUF3358); TIGRFAM: aminopeptidase N, Streptomyces lividans type.
 
   
 0.515
Arch_1734
Hypothetical protein; InterPro IPR013519; KEGG: hau:Haur_4585 FG-GAP repeat-containing protein; SPTR: D0YPS4 FG-GAP repeat protein; TIGRFAM: LPXTG-motif cell wall anchor domain.
  
    0.456
Arch_1735
Integrin alpha beta-propellor repeat protein; InterPro IPR013519; KEGG: ITGA1; integrin, alpha 1; K06480 integrin alpha 1; SMART: Integrin alpha beta-propellor repeat protein; SPTR: C2KTJ5 FG-GAP repeat domain protein.
  
    0.456
Arch_1736
LPXTG-motif cell wall anchor domain protein; InterPro IPR008969:IPR008454:IPR019931; KEGG: dsh:Dshi_3592 hypothetical protein; PFAM: Cna B domain protein; SPTR: A8LQ85 Putative uncharacterized protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: Cna protein B-type domain; TIGRFAM: LPXTG-motif cell wall anchor domain.
  
    0.456
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
    0.453
Arch_0167
Prolyl oligopeptidase; COGs: COG1505 Serine protease of the peptidase family S9A; InterPro IPR001375:IPR004106:IPR002470; KEGG: sml:Smlt4084 putative exported oligopeptidase; PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; PRIAM: Prolyl oligopeptidase; SPTR: B2FHW1 Putative exported oligoPEPTIDASE; PFAM: Prolyl oligopeptidase, N-terminal beta-propeller domain; Prolyl oligopeptidase family.
 
  
 0.415
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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