STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0544Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR013838:IPR000843:IPR001761:IPR010982; KEGG: rop:ROP_52910 putative LacI family transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: A7BCA6 Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family. (331 aa)    
Predicted Functional Partners:
Arch_1478
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR010982; KEGG: sco:SCO5692 transcriptional regulator; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: C0W8S7 Regulatory protein LacI family protein; PFAM: Bacterial regulatory proteins, lacI family; family.
  
     0.771
Arch_1488
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR010982; KEGG: sth:STH770 LacI family transcriptional repressor; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: C0W1U4 Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family.
  
     0.742
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
   
   0.686
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
   
   0.491
Arch_1122
Dihydroxyacetone kinase, phosphotransfer subunit; COGs: COG3412 conserved hypothetical protein; InterProIPR000032:IPR004701:IPR012844:IPR005698:IPR 001020; KEGG: ecm:EcSMS35_4856 phosphoenolpyruvate-protein phosphotransferase PtnE; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; SPTR: D0YPG5 PTS-dependent dihydroxyacetone kinase, DhaM subunit; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; PFAM: PTS system fructose IIA component; PTS HPr component phosphorylation site; TIGRFAM: dihydroxyacetone kinase, phosphotr [...]
   
 
 0.462
Arch_1461
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR000032:IPR005698:IPR001020; KEGG: cef:CE1830 putative PTS phosphohistidine-containing protein; PFAM: phosphoryl transfer system HPr; SPTR: A7BEU7 Putative uncharacterized protein; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
   
 
 0.459
Arch_0545
Major facilitator superfamily MFS_1; COGs: COG2271 Sugar phosphate permease; InterPro IPR011701:IPR016196; KEGG: esi:Exig_2601 sugar phosphate antiporter; PFAM: major facilitator superfamily MFS_1; SPTR: A7BCA4 Putative uncharacterized protein; PFAM: Major Facilitator Superfamily.
       0.441
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
   0.429
Arch_0546
Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760; KEGG: lin:lin1054 hypothetical protein; PFAM: inositol monophosphatase; SPTR: A7BCA5 Putative uncharacterized protein; PFAM: Inositol monophosphatase family.
       0.416
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
  
  
 0.414
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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