STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Arch_0547AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845:IPR000873; KEGG: jde:Jden_0962 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: D0WRA5 Putative CoA ligase; PFAM: AMP-binding enzyme. (608 aa)    
Predicted Functional Partners:
Arch_0659
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR018062:IPR020845:IPR000873; KEGG: saq:Sare_2221 acyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: D0WQX6 CoA ligase; PFAM: AMP-binding enzyme.
 
 
0.932
Arch_1363
COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR006092:IPR006091:IPR006090:IPR013786:IPR 013764:IPR009100:IPR009075; KEGG: drm:Dred_0570 crotonobetainyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain protein; SPTR: D0WP06 Crotonobetainyl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
 
 
 0.570
Arch_0284
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: bcv:Bcav_3247 O-succinylbenzoic acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: D0WMF4 O-succinylbenzoate--CoA ligase; PFAM: AMP-binding enzyme.
 
 
 0.532
Arch_0548
Hypothetical protein; KEGG: bfa:Bfae_03100 predicted membrane protein; SPTR: C7MGJ5 Predicted membrane protein.
       0.527
arc
AAA ATPase central domain protein; COGs: COG1222 ATP-dependent 26S proteasome regulatory subunit; InterPro IPR003960:IPR003593:IPR003959; KEGG: xce:Xcel_1485 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: C1RM61 ATP-dependent 26S proteasome regulatory subunit; PFAM: ATPase family associated with various cellular activities (AAA).
    
  0.500
rplE
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
   
 
 0.499
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.490
Arch_1628
COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: pac:PPA2237 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: D0WJT9 Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
    
 0.484
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.479
valS
tRNA synthetase valyl/leucyl anticodon-binding protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner.
  
    0.446
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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