STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0555COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: krh:KRH_11260 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: C0W772 Nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. (138 aa)    
Predicted Functional Partners:
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
  0.963
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
  0.957
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.954
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
 0.944
rpsB
COGs: COG0052 Ribosomal protein S2; InterPro IPR018130:IPR001865:IPR005706; KEGG: xce:Xcel_1180 ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: C0W045 Ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
   
 0.943
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
  0.938
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.933
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136:IPR000623:IPR011994; KEGG: jde:Jden_1271 cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; SPTR: D0WMU4 Prephenate dehydrogenase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
  
 
 0.932
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
  0.932
rpsI
COGs: COG0103 Ribosomal protein S9; InterPro IPR000754:IPR014721:IPR020568:IPR020574; KEGG: xce:Xcel_0662 ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: A7B9L2 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family.
  
  0.928
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.